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Aplasmomycin
Names
IUPAC name
sodium;(6R,9E,12R,14S,17R,25S,26R,28S,29E,32R,34S,37R)-12,32-dihydroxy-6,13,13,17,26,33,33,37-octamethyl-4,7,19,21,24,27,38,39,41,42-decaoxa-20-boranuidaoctacyclo[18.17.1.11,34.12,20.15,8.114,18.125,28.018,22]tritetraconta-9,29-diene-3,23-dione
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C40H60BO14.Na/c1-21-15-17-31-37(5,6)29(42)13-9-11-26-20-28(24(4)47-26)49-36(45)34-40-22(2)16-18-32(51-40)38(7,8)30(43)14-10-12-25-19-27(23(3)46-25)48-35(44)33-39(21,50-31)54-41(52-33,53-34)55-40;/h9-12,21-34,42-43H,13-20H2,1-8H3;/q-1;+1/b11-9+,12-10+;/t21-,22-,23-,24-,25-,26?,27+,28?,29-,30-,31+,32+,33?,34?,39?,40?,41?;/m1./s1
    Key: GEIYDRPAWIMINR-QLICSODISA-N
  • [B-]123O[C@]45O[C@H](C([C@@H](C/C=C/[C@H]6O[C@@H]([C@H](C6)OC(=O)[C@H](O1)[C@]7(O2)O[C@H](C([C@@H](C/C=C/[C@H]8O[C@@H]([C@H](C8)OC(=O)[C@@H]4O3)C)O)(C)C)CC[C@H]7C)C)O)(C)C)CC[C@H]5C.[Na+]
Properties
C40H60BNaO14
Molar mass 798.71 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Aplasmomycin is an antibiotic with antimalarial activity isolated from Streptomycete.[1]

References

[edit]
  1. ^ Okami, Y; Okazaki, T; Kitahara, T; Umezawa, H (1976). "Studies on marine microorganisms. V. A new antibiotic, aplasmomycin, produced by a streptomycete isolated from shallow sea mud". J Antibiot (Tokyo). 29 (10): 1019–25. doi:10.7164/antibiotics.29.1019. PMID 994322.


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