| Acronym | FFM |
|---|---|
| Uses | Allows biological samples to develop in free fall, thus mitigating the effect of gravity. |
| Inventor | D. Mesland |
| Related items | Clinostat, Random positioning machine, Large diameter centrifuge |
A free fall machine (FFM) is a mechanism designed to permit the development of small biological samples, such as cell cultures, with a simulated effect of micro-gravity under free fall conditions.[1]
Description
[edit]The free fall machine (FFM) addresses some of the problems of the simple horizontal clinostat or random positioning machines (RPM). In a typical machine samples are allowed to cycle between free fall for about a metre down a column (micro-gravity simulation, near "0 g") and a "bounce" back to the top of the column that is intended to be so fast (c. 20 g for 20 ms) that it is undetected by the biological sample. The sample therefore experiences an average gravity of near 0 g.
Long duration of hyper-gravity is often simulated by machines such as the large diameter centrifuge (LDC) at ESA. To simulate partial-gravity (between simulated 0 and Earth's gravity, 1, such as Mars or Moon gravitational strengths) conditions, an RPM can also be used.
See also
[edit]References
[edit]- ^ Schwarzenberg M, Pippia P, Meloni MA, Cossu G, Cogoli-Greuter M, Cogoli A. (1999). Signal transduction in T lymphocytes--a comparison of the data from space, the free fall machine and the random positioning machine. Adv Space Res. 24(6): 793-800
External links
[edit]- ETH Space Biology Free Fall Machine
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