Lou Antonio (gebore 23 Januarie 1934) is 'n Amerikaanse regisseur, akteur, en vervaardiger. Hy is bekend vir sy rolle in die rolprent Cool Hand Luke (1967) en in die televisiereekse Star Trek (1966), Picket Fences (1992), en Chicago Hope (1994).
- 1967: Cool Hand Luke
- 1968: Mission Batangas
- 1978: The Gypsy Warriors
- 2010: From the Midst of Pain
- 2013: From Cheesecake to Cheesecake: The Joy Harmon Story
- 1961: Great Ghost Tales
- 1966: Star Trek
- 1972: The Snoop Sisters
- 1977: Dog and Cat
- 1979: Makin' It
- 1992: Picket Fences
- 1994: Chicago Hope
- 1970: Sole Survivor
- 1974: Fools, Females and Fun
- 1974: Love Is Not Forever
- 1975: Someone I Touched
- 1977: Dog and Cat
- 1977: The Girl in the Empty Grave
- 1977: Something for Joey
- 1978: The Critical List
- 1978: A Real American Hero
- 1979: Breaking Up Is Hard to Do
- 1979: Silent Victory: The Kitty O'Neil Story
- 1979: The Chinese Typewriter
- 1979: Heaven on Earth
- 1981: The Star Maker
- 1981: We're Fighting Back
- 1981: The Steeler and the Pittsburgh Kid
- 1981: Gabe and Walker
- 1982: Something So Right
- 1983: Between Friends
- 1984: A Good Sport
- 1984: Rearview Mirror
- 1984: Threesome
- 1985: Thirteen at Dinner
- 1986: One Terrific Guy
- 1987: Mayflower Madam
- 1987: Pals
- 1989: Dark Holiday
- 1989: The Outside Woman
- 1990: Face to Face
- 1990: Sporting Chance
- 1991: The Last Prostitute
- 1991: Lies Before Kisses
- 1991: The Rape of Doctor Willis
- 1991: This Gun for Hire
- 1992: Nightmare in the Daylight
- 1992: A Taste for Killing
- 1993: The Contender
- 1999: The Force
- 2000: David Dukes Memorial
- 2008: A Natural Born World-Shaker: Making 'Cool Hand Luke'
