Mary-Margaret Humes (gebore 4 April 1954) is 'n Amerikaanse aktrise. Sy is bekend vir haar rolle in die rolprent History of the World: Part I (1981) en in die televisiereekse Eerie, Indiana (1991) en Dawson's Creek (1998).
- 1981: History of the World: Part I
- 2015: Chasing Eagle Rock
- 2017: Christmas Crime Story
- 1991: Eerie, Indiana
- 1993: Time Trax
- 1995: Land's End
- 1998: Dawson's Creek
- 1984: Velvet
- 1995: Gramps
- 1999: Dawson's Creek: Behind the Scenes
- 1999: Songs from Dawson's Creek
- 2000: Rivals
- 2001: Dying to Dance
- 2001: Motocrossed
- 2010: The Republic
- 2014: The Girl He Met Online
- 2018: Home by Spring
