• ربط دي إن إي• protein dimerization activity• transcription factor binding• chromatin binding• GO:0001078، GO:0001214، GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific• double-stranded DNA binding• GO:0001200، GO:0001133، GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific• RNA polymerase II transcription regulatory region sequence-specific DNA binding• GO:0001106 transcription corepressor activity• sequence-specific DNA binding• sequence-specific double-stranded DNA binding
• بلازم نووي• نواة• مكون خلوي
• Notch signaling pathway• auditory receptor cell fate determination• establishment of epithelial cell polarity• تمايز خلوي• negative regulation of astrocyte differentiation• regulation of inner ear auditory receptor cell differentiation• GO:0009373 ضبط نسخ الدنا• negative regulation of neuron differentiation• inner ear receptor cell stereocilium organization• comma-shaped body morphogenesis• metanephric nephron tubule morphogenesis• chondrocyte differentiation• central nervous system myelination• GO:1901227 negative regulation of transcription by RNA polymerase II• cell maturation• negative regulation of forebrain neuron differentiation• نسخ الدنا• نماء عصبي• negative regulation of stem cell differentiation• neuronal stem cell population maintenance• GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated• نمو متعدد الخلايا• glial cell fate commitment• telencephalon development• brain development• inner ear auditory receptor cell differentiation• التصاق الخلايا• astrocyte differentiation• تَكوّن الغُضروف• forebrain radial glial cell differentiation• regulation of myelination• negative regulation of oligodendrocyte differentiation• S-shaped body morphogenesis• neural tube development• neuron differentiation• ضبط زيادي للتكاثر الخلوي• positive regulation of BMP signaling pathway• negative regulation of pro-B cell differentiation• regulation of cell differentiation• smoothened signaling pathway• oligodendrocyte development• camera-type eye development• specification of loop of Henle identity• regulation of epithelial cell proliferation• GO:0045996 negative regulation of transcription, DNA-templated• negative regulation of inner ear receptor cell differentiation• regulation of neurogenesis• positive regulation of receptor signaling pathway via JAK-STAT• positive regulation of Notch signaling pathway• GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني• positive regulation of smooth muscle cell proliferation• positive regulation of tyrosine phosphorylation of STAT protein• GO:0034622 protein-containing complex assembly• تكون الجسيدات• central nervous system development• نقل شاردة الكالسيوم• negative regulation of inner ear auditory receptor cell differentiation
Q5TA89
P70120
XM_005244751 NM_001010926، XM_005244751
XM_006538562، NM_001370755 NM_010419، XM_006538562، NM_001370755
XP_005244808 NP_001010926، XP_005244808
XP_006538625، NP_001357684 NP_034549، XP_006538625، NP_001357684
HES5 هوا چين موجود فى الانسان العاقل بيشفره Hes family bHLH transcription factor 5.[1][2][3]