1PDG, 3MJG, 4HQU, 4HQX, 4QCI
• protein homodimerization activity• protein heterodimerization activity• chemoattractant activity• platelet-derived growth factor receptor binding• platelet-derived growth factor binding• superoxide-generating NADPH oxidase activator activity• growth factor activity• identical protein binding• collagen binding• GO:0001948، GO:0016582 ربط بروتيني• phosphatidylinositol-4,5-bisphosphate 3-kinase activity
• platelet alpha granule lumen• سيتوبلازم• الفراغ خارج الخلية• Golgi membrane• basolateral plasma membrane• cell surface• endoplasmic reticulum lumen• غشاء• GO:0005578 نسيج بيني خارج الخلية• خارج خلوي• تجويف غولجي• collagen-containing extracellular matrix
• activation of protein kinase B activity• positive regulation of DNA biosynthetic process• positive regulation of chemotaxis• cellular response to growth factor stimulus• positive regulation of protein tyrosine kinase activity• peptidyl-tyrosine phosphorylation• positive regulation of cell division• نماء القلب• positive regulation of glomerular filtration• positive regulation of mitotic nuclear division• positive regulation of MAP kinase activity• positive regulation of metanephric mesenchymal cell migration• positive regulation of hyaluronan biosynthetic process• MAPK cascade• protein phosphorylation• positive regulation of glomerular mesangial cell proliferation• cellular response to mycophenolic acid• positive regulation of fibroblast proliferation• activation of protein kinase activity• نمو متعدد الخلايا• positive regulation of protein autophosphorylation• positive regulation of reactive oxygen species metabolic process• عملية التمثيل الغذائي لأنواع الأكسجين التفاعلية• GO:0045996 negative regulation of transcription, DNA-templated• protein kinase C signaling• metanephric glomerular mesangial cell development• negative regulation of phosphatidylinositol biosynthetic process• response to wounding• positive regulation of phosphatidylinositol 3-kinase activity• cell chemotaxis• positive regulation of ERK1 and ERK2 cascade• platelet degranulation• ضبط زيادي للتكاثر الخلوي• positive regulation of DNA replication• GO:1901313 positive regulation of gene expression• embryonic placenta development• تأشير نظير صماوي• monocyte chemotaxis• positive regulation of endothelial cell proliferation• positive regulation of phosphatidylinositol 3-kinase signaling• positive regulation of calcium ion import• GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated• GO:0035404 peptidyl-serine phosphorylation• positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway• positive regulation of blood vessel endothelial cell migration• تكون الدم• positive regulation of cell migration• positive regulation of peptidyl-tyrosine phosphorylation• extracellular matrix organization• negative regulation of protein binding• positive regulation of MAPK cascade• positive regulation of cyclin-dependent protein serine/threonine kinase activity• negative regulation of platelet activation• phosphatidylinositol phosphate biosynthetic process• positive regulation of vascular associated smooth muscle cell migration• positive chemotaxis• negative regulation of vascular associated smooth muscle cell differentiation• interleukin-18-mediated signaling pathway• positive regulation of pri-miRNA transcription by RNA polymerase II• negative regulation of pri-miRNA transcription by RNA polymerase II• negative regulation of gene expression• positive regulation of smooth muscle cell migration• positive regulation of smooth muscle cell proliferation• positive regulation of vascular associated smooth muscle cell dedifferentiation• platelet-derived growth factor receptor signaling pathway• positive regulation of vascular associated smooth muscle cell proliferation• negative regulation of platelet-derived growth factor receptor-beta signaling pathway• regulation of signaling receptor activity• positive regulation of protein kinase B signaling
P01127
P31240
NM_002608، XM_047441393، XM_047441394 NM_033016، NM_002608، XM_047441393، XM_047441394
XM_006520592، XM_017316502 NM_011057، XM_006520592، XM_017316502
NP_148937 NP_002599، NP_148937
XP_006520655، XP_030104269، XP_030104270، XP_030104271، XP_036015133، XP_036015134 NP_035187، XP_006520655، XP_030104269، XP_030104270، XP_030104271، XP_036015133، XP_036015134
PDGFB هوا چين موجود فى الانسان العاقل بيشفره Platelet derived growth factor subunit B.[1][2][3]