PVRIG

PVRIG
Identifikatori
Aliasi	PVRIG
Vanjski ID-jevi	OMIM: 617012 MGI: 5596028 HomoloGene: 78229 GeneCards: PVRIG
Lokacija gena (čovjek) Hrom. Hromosom 7 (čovjek)[1] Bend 7q22.1 Početak 100,218,241 bp[1] Kraj 100,221,490 bp[1]
Lokacija gena (miš) Hrom. Hromosom 5 (miš)[2] Bend 5 G2|5 Početak 138,340,223 bp[2] Kraj 138,341,819 bp[2]
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • phosphatase binding • signaling receptor activity Ćelijska komponenta • membrana • integral component of membrane • ćelijska membrana Biološki proces • negative regulation of T cell receptor signaling pathway • GO:0072468 Transdukcija signala Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	79037	102640920
Ensembl	ENSG00000213413	ENSMUSG00000109713
UniProt	Q6DKI7	A0A1B0GS01
RefSeq (mRNK)	NM_024070 NM_001387134 NM_001397246	NM_001378438
RefSeq (bjelančevina)	NP_076975	NP_001365367
Lokacija (UCSC)	Chr 7: 100.22 – 100.22 Mb	Chr 5: 138.34 – 138.34 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Poliovirusni receptor srodan imunoglobulinu sa domenom jest protein koji je kod ljudi kodiran genom PVRIG.^[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 326 aminokiselina, а molekulska težina 34.344 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MRTEAQVPAL		QPPEPGLEGA		MGHRTLVLPW		VLLTLCVTAG		TPEVWVQVRM
EATELSSFTI		RCGFLGSGSI		SLVTVSWGGP		NGAGGTTLAV		LHPERGIRQW
APARQARWET		QSSISLILEG		SGASSPCANT		TFCCKFASFP		EGSWEACGSL
PPSSDPGLSA		PPTPAPILRA		DLAGILGVSG		VLLFGCVYLL		HLLRRHKHRP
APRLQPSRTS		PQAPRARAWA		PSQASQAALH		VPYATINTSC		RPATLDTAHP
HGGPSWWASL		PTHAAHRPQG		PAAWASTPIP		ARGSFVSVEN		GLYAQAGERP
PHTGPGLTLF		PDPRGPRAME		GPLGVR

Reference

1. GRCh38: Ensembl release 89: ENSG00000213413 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000109713 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Poliovirus receptor related immunoglobulin domain containing". Pristupljeno 15. 3. 2016.
6. "UniProt, Q6DKI7" (jezik: engleski). Pristupljeno 28. 9. 2021.