ACTG2

ACTG2
Dynodwyr
Cyfenwau	ACTG2, ACT, ACTA3, ACTE, ACTL3, ACTSG, VSCM, actin, gamma 2, smooth muscle, enteric, actin gamma 2, smooth muscle, VSCM1, MMIHS5
Dynodwyr allanol	OMIM: 102545 HomoloGene: 123845 GeneCards: ACTG2
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • ATP binding;
Cydrannau o'r gell	• cytoplasm; • filopodium; • cell body; • myosin filament; • cytosol; • blood microparticle; • extracellular exosome; • Cytosgerbwd; • cyrion cell; • lamellipodium; • extracellular space;
Prosesau biolegol	• mesenchyme migration; • GO:1901313 positive regulation of gene expression; • muscle contraction;
	Sources:Amigo / QuickGO
Orthologau
	72
	n/a
	ENSG00000163017
	n/a
	P63267
	n/a
	NM_001615; NM_001199893
	n/a
	NP_001186822; NP_001606
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ACTG2 yw ACTG2 a elwir hefyd yn Actin, gamma-enteric smooth muscle ac Actin, gamma 2, smooth muscle, enteric (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p13.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ACTG2.

ACT
ACTE
VSCM
ACTA3
ACTL3
ACTSG

Llyfryddiaeth

"A plausible role for actin gamma smooth muscle 2 (ACTG2) in small intestinal neuroendocrine tumorigenesis. ". BMC Endocr Disord. 2016. PMID 27107594.
"Mutation in Actin Î³-2 Responsible for Megacystis Microcolon Intestinal Hypoperistalsis Syndrome in 4 Chinese Patients. ". J Pediatr Gastroenterol Nutr. 2016. PMID 27007401.
"Variants of the ACTG2 gene correlate with degree of severity and presence of megacystis in chronic intestinal pseudo-obstruction. ". Eur J Hum Genet. 2016. PMID 26813947.
"ACTG2 variants impair actin polymerization in sporadic Megacystis Microcolon Intestinal Hypoperistalsis Syndrome. ". Hum Mol Genet. 2016. PMID 26647307.
"Gamma-smooth muscle actin expression is associated with epithelial-mesenchymal transition and stem-like properties in hepatocellular carcinoma.". PLoS One. 2015. PMID 26110787.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] ACTG2 - Cronfa NCBI

[1]

[2]