AP1B1

AP1B1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	4HMY, 4P6Z
Dynodwyr
Cyfenwau	AP1B1, ADTB1, AP105A, BAM22, CLAPB2, adaptor related protein complex 1 beta 1 subunit, adaptor related protein complex 1 subunit beta 1, KIDAR
Dynodwyr allanol	OMIM: 600157 HomoloGene: 21972 GeneCards: AP1B1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• transporter activity; • GO:0001948, GO:0016582 protein binding; • protein kinase binding; • clathrin binding;
Cydrannau o'r gell	• trans-Golgi network membrane; • bilen; • Golgi membrane; • lysosomal membrane; • clathrin-coated vesicle membrane; • membrane coat; • cytoplasmic vesicle membrane; • GO:0016023 cytoplasmic vesicle; • clathrin adaptor complex; • Golgi apparatus; • cytosol; • intracellular membrane-bounded organelle;
Prosesau biolegol	• antigen processing and presentation of exogenous peptide antigen via MHC class II; • GO:0019049, GO:0030683 mitigation of host defenses by virus; • heart development; • determination of left/right symmetry; • protein transport; • intracellular protein transport; • vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologau
	162
	n/a
	ENSG00000100280
	n/a
	Q10567
	n/a
	NM_145730; NM_001127; NM_001166019
	n/a
NP_001118; NP_001159491; NP_663782; NP_001365491; NP_001365492;
	NP_001365493; NP_001365494; NP_001365495
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AP1B1 yw AP1B1 a elwir hefyd yn AP-1 complex subunit beta-1 ac Adaptor related protein complex 1 beta 1 subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AP1B1.

ADTB1
BAM22
AP105A
CLAPB2

Llyfryddiaeth

"Structure of the promoter and genomic organization of the human beta'-adaptin gene (BAM22) from chromosome 22q12. ". Genomics. 1996. PMID 8812422.
"Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1. ". Mol Biol Cell. 2015. PMID 25739457.
"Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells. ". Traffic. 2013. PMID 23205726.
"Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene. ". Hum Mol Genet. 1994. PMID 7987321.
"ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells.". J Cell Biol. 2011. PMID 21444685.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] AP1B1 - Cronfa NCBI

[1]

[2]