AP1G1

AP1G1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1IU1
Dynodwyr
Cyfenwau	AP1G1, ADTG, CLAPG1, adaptor related protein complex 1 gamma 1 subunit, adaptor related protein complex 1 subunit gamma 1, USRISD
Dynodwyr allanol	OMIM: 603533 HomoloGene: 47995 GeneCards: AP1G1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• transporter activity; • GTP-dependent protein binding; • GO:0001948, GO:0016582 protein binding; • kinesin binding;
Cydrannau o'r gell	• recycling endosome; • clathrin-coated endocytic vesicle membrane; • Golgi apparatus; • trans-Golgi network membrane; • bilen; • intracellular membrane-bounded organelle; • Golgi membrane; • lysosomal membrane; • AP-type membrane coat adaptor complex; • clathrin-coated vesicle membrane; • membrane coat; • cytoplasmic vesicle membrane; • GO:0016023 cytoplasmic vesicle; • clathrin-coated vesicle; • clathrin adaptor complex; • cytoplasm; • cytosol; • AP-1 adaptor complex;
Prosesau biolegol	• antigen processing and presentation of exogenous peptide antigen via MHC class II; • GO:0019049, GO:0030683 mitigation of host defenses by virus; • Golgi to lysosome transport; • positive regulation of natural killer cell degranulation; • melanosome organization; • endosome to melanosome transport; • protein transport; • intracellular protein transport; • positive regulation of natural killer cell mediated cytotoxicity; • vesicle-mediated transport; • GO:0015915 transport;
	Sources:Amigo / QuickGO
Orthologau
	164
	n/a
	ENSG00000166747
	n/a
	O43747
	n/a
	NM_001128; NM_001030007
	n/a
	NP_001025178; NP_001119
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AP1G1 yw AP1G1 a elwir hefyd yn Adaptor related protein complex 1 gamma 1 subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q22.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AP1G1.

ADTG
CLAPG1

Llyfryddiaeth

"Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes. ". EMBO J. 2003. PMID 12773381.
"Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain. ". J Biochem. 2002. PMID 11872161.
"Rab4b controls an early endosome sorting event by interacting with the Î³-subunit of the clathrin adaptor complex 1. ". J Cell Sci. 2013. PMID 24006255.
"Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation. ". J Biol Chem. 2006. PMID 16867982.
"AP1G1 is involved in cetuximab-mediated downregulation of ASCT2-EGFR complex and sensitization of human head and neck squamous cell carcinoma cells to ROS-induced apoptosis.". Cancer Lett. 2017. PMID 28823958.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] AP1G1 - Cronfa NCBI

[1]

[2]