APRT

APRT
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1ZN9, 1ORE, 1ZN7, 1ZN8, 4X44, 4X45
Dynodwyr
Cyfenwau	APRT, AMP, APRTD, adenine phosphoribosyltransferase
Dynodwyr allanol	OMIM: 102600 HomoloGene: 413 GeneCards: APRT
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• glycosyltransferase activity; • transferase activity; • adenine binding; • adenine phosphoribosyltransferase activity; • AMP binding;
Cydrannau o'r gell	• nucleoplasm; • extracellular exosome; • extracellular region; • cytoplasm; • cytosol; • secretory granule lumen;
Prosesau biolegol	• grooming behavior; • nucleoside metabolic process; • purine-containing compound salvage; • lactation; • purine ribonucleoside salvage; • adenine salvage; • adenine metabolic process; • cellular response to insulin stimulus; • AMP salvage; • neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologau
	353
	n/a
	ENSG00000198931
	n/a
	P07741
	n/a
	NM_001030018; NM_000485
	n/a
	NP_000476; NP_001025189
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn APRT yw APRT a elwir hefyd yn Adenine phosphoribosyltransferase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q24.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APRT.

AMP
APRTD

Llyfryddiaeth

"Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation. ". BMC Nephrol. 2014. PMID 24986359.
Adenine Phosphoribosyltransferase Deficiency. 1993. PMID 22934314.
"A Japanese boy with adenine phosphoribosyltransferase (APRT) deficiency caused by compound heterozygosity including a novel missense mutation in APRT gene. ". Acta Paediatr. 2011. PMID 21635362.
"The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP. ". Mol Cell Biochem. 2009. PMID 19399589.
"Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism.". J Biomol Struct Dyn. 2008. PMID 18399692.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] APRT - Cronfa NCBI

[1]

[2]