ARF4

ARF4
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1Z6X
Dynodwyr
Cyfenwau	ARF4, ARF2, ADP ribosylation factor 4
Dynodwyr allanol	OMIM: 601177 HomoloGene: 55593 GeneCards: ARF4
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • epidermal growth factor receptor binding; • GTP binding; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• cytosol; • Golgi apparatus; • bilen; • dendritic spine; • intracellular anatomical structure; • ruffle membrane; • extracellular exosome; • GO:0005578 extracellular matrix; • cytoplasm; • Cellbilen; • glutamatergic synapse;
Prosesau biolegol	• protein ADP-ribosylation; • small GTPase mediated signal transduction; • negative regulation of apoptotic process; • GO:1904489 regulation of reactive oxygen species metabolic process; • endoplasmic reticulum to Golgi vesicle-mediated transport; • activation of phospholipase D activity; • protein transport; • cell migration; • vesicle-mediated transport; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; • GO:0015915 transport; • dendritic spine development; • intracellular protein transport; • Golgi to plasma membrane transport; • epidermal growth factor receptor signaling pathway; • brain development; • learning; • apical protein localization; • establishment or maintenance of epithelial cell apical/basal polarity; • response to axon injury; • GO:1904739 regulation of synapse organization; • protein localization to cilium; • regulation of postsynapse organization;
	Sources:Amigo / QuickGO
Orthologau
	378
	n/a
	ENSG00000168374
	n/a
	P18085
	n/a
	NM_001660
	n/a
	NP_001651
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARF4 yw ARF4 a elwir hefyd yn ADP ribosylation factor 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p14.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARF4.

ARF2

Llyfryddiaeth

"Role of ARF4L in recycling between endosomes and the plasma membrane. ". Cell Mol Neurobiol. 2004. PMID 15049518.
"Cloning and characterization of the human ADP-ribosylation factor 4 gene. ". Gene. 1999. PMID 10524252.
"Human ADP-ribosylation factor 4 (ARF4) gene. Map position 3p14.1. ". Chromosome Res. 1998. PMID 10099884.
"Differential gene expression in SV40-mediated immortalization of human fibroblasts. ". J Cell Physiol. 1997. PMID 9180902.
"A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.". Nat Cell Biol. 2013. PMID 24185178.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] ARF4 - Cronfa NCBI

[1]

[2]