ARF5

ARF5
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2B6H
Dynodwyr
Cyfenwau	ARF5, ADP ribosylation factor 5
Dynodwyr allanol	OMIM: 103188 HomoloGene: 129625 GeneCards: ARF5
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • GTP binding; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• cytoplasm; • perinuclear region of cytoplasm; • Cellbilen; • Golgi apparatus; • extracellular exosome; • intracellular anatomical structure; • bilen;
Prosesau biolegol	• protein transport; • small GTPase mediated signal transduction; • vesicle-mediated transport; • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; • GO:0015915 transport; • intracellular protein transport; • Golgi to plasma membrane transport;
	Sources:Amigo / QuickGO
Orthologau
	381
	n/a
	ENSG00000004059
	n/a
	P84085
	n/a
	NM_001662
	n/a
	NP_001653
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARF5 yw ARF5 a elwir hefyd yn ADP ribosylation factor 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q32.1.^[2]

Llyfryddiaeth

"Localization and characterization of the human ADP-ribosylation factor 5 (ARF5) gene. ". Genomics. 1997. PMID 9169151.
"GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting. ". J Invest Dermatol. 2015. PMID 26000619.
"BRAG2/GEP100/IQSec1 interacts with clathrin and regulates α5β1 integrin endocytosis through activation of ADP ribosylation factor 5 (Arf5). ". J Biol Chem. 2012. PMID 22815487.
"Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. ". J Biol Chem. 2012. PMID 22105072.
"Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.". J Biol Chem. 1991. PMID 1993656.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] ARF5 - Cronfa NCBI

[1]

[2]