ARL8A

ARL8A
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1ZD9, 2H18, 4ILE
Dynodwyr
Cyfenwau	ARL8A, ARL10B, GIE2, ADP ribosylation factor like GTPase 8A
Dynodwyr allanol	OMIM: 616597 HomoloGene: 23600 GeneCards: ARL8A
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • alpha-tubulin binding; • GTP binding; • GO:0001948, GO:0016582 protein binding; • beta-tubulin binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• cytoplasm; • spindle midzone; • lysosomal membrane; • endosome; • lysosome; • midbody; • extracellular exosome; • intracellular anatomical structure; • bilen; • late endosome membrane; • Cellbilen; • azurophil granule membrane; • ficolin-1-rich granule membrane; • vacuolar membrane; • axon cytoplasm; • spindle; • Cytosgerbwd; • cell junction; • axon; • cell projection; • synapse;
Prosesau biolegol	• Cellraniad; • small GTPase mediated signal transduction; • cell cycle; • chromosome segregation; • neutrophil degranulation; • anterograde axonal transport; • protein transport;
	Sources:Amigo / QuickGO
Orthologau
	127829
	n/a
	ENSG00000143862
	n/a
	Q96BM9
	n/a
	NM_138795; NM_001256129
	n/a
	NP_001243058; NP_620150
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARL8A yw ARL8A a elwir hefyd yn ADP ribosylation factor like GTPase 8A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q32.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARL8A.

GIE2
ARL10B

Llyfryddiaeth

"Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein. ". J Biol Chem. 2004. PMID 14871887.
"BORC, a multisubunit complex that regulates lysosome positioning. ". Dev Cell. 2015. PMID 25898167.
"An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility. ". J Cell Sci. 2006. PMID 16537643.
"Exploration of panviral proteome: high-throughput cloning and functional implications in virus-host interactions. ". Theranostics. 2014. PMID 24955142.
"Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.". J Cell Sci. 2004. PMID 15331635.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] ARL8A - Cronfa NCBI

[1]

[2]