ARL8B

ARL8B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2AL7
Dynodwyr
Cyfenwau	ARL8B, ARL10C, Gie1, ADP ribosylation factor like GTPase 8B
Dynodwyr allanol	OMIM: 616596 HomoloGene: 10056 GeneCards: ARL8B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GDP binding • alpha-tubulin binding • GTP binding • GO:0006184 GTPase activity • beta-tubulin binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • endosome • bilen • late endosome membrane • spindle • intracellular anatomical structure • midbody • spindle midzone • lysosome • extracellular exosome • Cytosgerbwd • lysosomal membrane • vacuolar membrane • axon • synapse • axon cytoplasm • cell junction • cell projection Prosesau biolegol • chromosome segregation • small GTPase mediated signal transduction • Cellraniad • cell cycle • lysosome localization • anterograde axonal transport • protein transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55207	n/a
Ensembl	ENSG00000134108	n/a
UniProt	Q9NVJ2	n/a
RefSeq (mRNA)	NM_018184	n/a
RefSeq (protein)	NP_060654	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARL8B yw ARL8B a elwir hefyd yn ADP ribosylation factor like GTPase 8B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p26.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARL8B.

• Gie1
• ARL10C

Llyfryddiaeth

• "The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes. ". Biochem Biophys Res Commun. 2006. PMID 16650381.
• "LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning. ". J Cell Biol. 2017. PMID 28993467.
• "The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes. ". J Cell Sci. 2015. PMID 25908847.
• "Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity. ". Mol Biol Cell. 2013. PMID 24088571.
• "Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b.". Immunity. 2011. PMID 21802320.

Cyfeiriadau

1. "Human PubMed Reference:".
2. ARL8B - Cronfa NCBI