| ATF1 |
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| Dynodwyr |
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| Cyfenwau | ATF1, EWS-FUS/ATF-1, TREB36, activating transcription factor 1 |
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| Dynodwyr allanol | OMIM: 123803 HomoloGene: 3790 GeneCards: ATF1 |
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| Ontoleg y genyn |
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| Gweithrediad moleciwlaidd | • DNA binding
• sequence-specific DNA binding
• RNA polymerase II transcription regulatory region sequence-specific DNA binding
• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
• GO:0001948, GO:0016582 protein binding
• protein heterodimerization activity
• transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
• identical protein binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
• GO:0032403 protein-containing complex binding
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| Cydrannau o'r gell | • ATF1-ATF4 transcription factor complex
• transcription regulator complex
• nucleoplasm
• cnewyllyn cell
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| Prosesau biolegol | • GO:0009373 regulation of transcription, DNA-templated
• GO:1904578 response to organic cyclic compound
• transcription, DNA-templated
• positive regulation of DNA replication
• positive regulation of neuron projection development
• response to cobalt ion
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• transcription by RNA polymerase II
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
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| Sources:Amigo / QuickGO |
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| Orthologau |
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| Species | Bod dynol | Llygoden |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Lleoliad (UCSC) | n/a | n/a |
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| PubMed search | [1] | n/a |
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| Wicidata |
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Protein sy'n cael ei godio yn y corff dynol gan y genyn ATF1 yw ATF1 a elwir hefyd yn Activating transcription factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q13.12.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ATF1.
- TREB36
- EWS-ATF1
- FUS/ATF-1
- "5'-AMP-activated protein kinase-activating transcription factor 1 cascade modulates human monocyte-derived macrophages to atheroprotective functions in response to heme or metformin. ". Arterioscler Thromb Vasc Biol. 2013. PMID 24051143.
- "Activating transcription factor 1 is a prognostic marker of colorectal cancer. ". Asian Pac J Cancer Prev. 2012. PMID 22631637.
- "Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection. ". Circ Res. 2012. PMID 22052915.
- "Composition and function of AP-1 transcription complexes during muscle cell differentiation. ". J Biol Chem. 2002. PMID 11877423.
- "Promoter elements and transcription factors involved in differentiation-dependent human chorionic gonadotrophin-alpha messenger ribonucleic acid expression of term villous trophoblasts.". Endocrinology. 2000. PMID 11014230.
