ATP5F1B

ATP5F1B
Dynodwyr
Cyfenwau	ATP5F1B, ATPMB, ATPSB, HEL-S-271, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide, ATP synthase F1 subunit beta, ATP5B
Dynodwyr allanol	OMIM: 102910 HomoloGene: 1273 GeneCards: ATP5F1B
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • GO:0022891 transmembrane transporter activity; • transporter activity; • proton-transporting ATPase activity, rotational mechanism; • ATPase activity; • GO:0001948, GO:0016582 protein binding; • MHC class I protein binding; • hydrolase activity; • ATP binding; • angiostatin binding; • proton-transporting ATP synthase activity, rotational mechanism;
Cydrannau o'r gell	• mitochondrial proton-transporting ATP synthase complex; • bilen; • mitochondrial membranes; • myelin sheath; • Cellbilen; • cell surface; • mitochondrial matrix; • mitochondrial proton-transporting ATP synthase, catalytic core; • mitocondria; • mitochondrial inner membrane; • proton-transporting ATP synthase complex, catalytic core F(1); • mitochondrial nucleoid; • extracellular exosome; • cnewyllyn cell; • GO:0005578 extracellular matrix; • proton-transporting ATP synthase complex; • proton-transporting two-sector ATPase complex, catalytic domain;
Prosesau biolegol	• lipid metabolism; • mitochondrial ATP synthesis coupled proton transport; • mitochondrion organization; • regulation of intracellular pH; • cludo ïon; • generation of precursor metabolites and energy; • negative regulation of cell adhesion involved in substrate-bound cell migration; • ATP metabolic process; • angiogenesis; • osteoblast differentiation; • ATP synthesis coupled proton transport; • ATP biosynthetic process; • cristae formation; • positive regulation of blood vessel endothelial cell migration; • GO:0015915 transport; • cellular response to interleukin-7; • proton transmembrane transport;
	Sources:Amigo / QuickGO
Orthologau
	506
	n/a
	ENSG00000110955
	n/a
	P06576
	n/a
	NM_001686
	n/a
	NP_001677
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ATP5F1B yw ATP5F1B a elwir hefyd yn ATP synthase subunit beta, mitochondrial ac ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q13.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ATP5F1B.

ATP5B
ATPMB
ATPSB
HEL-S-271

Llyfryddiaeth

"Ectopic expression of the ATP synthase β subunit on the membrane of PC-3M cells supports its potential role in prostate cancer metastasis. ". Int J Oncol. 2017. PMID 28259978.
"Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase β Subunit. ". PLoS One. 2016. PMID 27532680.
"Hypermethylation of CpG sites at the promoter region is associated with deregulation of mitochondrial ATPsyn-β and chemoresistance in acute myeloid leukemia. ". Cancer Biomark. 2016. PMID 26835708.
"Deregulation of mitochondrial ATPsyn-β in acute myeloid leukemia cells and with increased drug resistance. ". PLoS One. 2013. PMID 24391795.
"Induction of ATP synthase β by H2O2 induces melanogenesis by activating PAH and cAMP/CREB/MITF signaling in melanoma cells.". Int J Biochem Cell Biol. 2013. PMID 23523934.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] ATP5F1B - Cronfa NCBI

[1]

[2]