BAIAP2

BAIAP2
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1WDZ, 1Y2O, 2YKT, 3RNJ, 4JS0
Dynodwyr
Cyfenwau	BAIAP2, BAP2, FLAF3, IRSP53, BAI1 associated protein 2, BAR/IMD domain containing adaptor protein 2, WAML
Dynodwyr allanol	OMIM: 605475 HomoloGene: 9697 GeneCards: BAIAP2
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• PDZ domain binding; • protein C-terminus binding; • GO:0001948, GO:0016582 protein binding; • identical protein binding; • cytoskeletal anchor activity; • proline-rich region binding; • cadherin binding involved in cell-cell adhesion; • transcription coregulator binding; • scaffold protein binding;
Cydrannau o'r gell	• cytosol; • cell projection; • GO:0097483, GO:0097481 postsynaptic density; • bilen; • filopodium; • ruffle; • dendritic spine; • secretory granule; • soma; • actin cytoskeleton; • neuron projection; • extracellular exosome; • Cytosgerbwd; • cytoplasm; • rough endoplasmic reticulum; • Golgi apparatus; • microtubule; • Cellbilen; • dendritic shaft; • neuron projection terminus; • excitatory synapse; • synaptic membrane; • postsynapse; • neuron projection branch point; • dendritic spine cytoplasm; • presynapse; • nucleoplasm; • Schaffer collateral - CA1 synapse; • glutamatergic synapse; • postsynaptic density, intracellular component; • presynaptic cytosol; • postsynaptic cytosol;
Prosesau biolegol	• GO:1901047 insulin receptor signaling pathway; • positive regulation of actin filament polymerization; • regulation of actin cytoskeleton organization; • response to bacterium; • axonogenesis; • Fc-gamma receptor signaling pathway involved in phagocytosis; • dendrite development; • actin filament bundle assembly; • regulation of synaptic plasticity; • vascular endothelial growth factor receptor signaling pathway; • actin crosslink formation; • regulation of cell shape; • plasma membrane organization; • positive regulation of actin cytoskeleton reorganization; • positive regulation of dendritic spine morphogenesis; • cell-cell adhesion; • brain development; • positive regulation of neuron projection development; • neuron differentiation; • protein localization to synapse; • cellular response to epidermal growth factor stimulus; • cellular response to L-glutamate; • positive regulation of excitatory postsynaptic potential; • modulation of chemical synaptic transmission; • modification of synaptic structure, modulating synaptic transmission; • regulation of modification of postsynaptic actin cytoskeleton;
	Sources:Amigo / QuickGO
Orthologau
	10458
	n/a
	ENSG00000175866
	n/a
	Q9UQB8
	n/a
	NM_001144888; NM_006340; NM_017450; NM_017451
	n/a
	NP_001138360; NP_006331; NP_059344; NP_059345
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BAIAP2 yw BAIAP2 a elwir hefyd yn BAI1 associated protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q25.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BAIAP2.

BAP2
FLAF3
IRSP53

Llyfryddiaeth

"Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli. ". Structure. 2011. PMID 21893288.
"[A molecular dynamics study of the interaction between domain I-BAR of the IRSp53 protein and negatively charged membranes]. ". Biofizika. 2011. PMID 21542353.
"IRSp53 senses negative membrane curvature and phase separates along membrane tubules. ". Nat Commun. 2015. PMID 26469246.
"IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders. ". Neuropharmacology. 2016. PMID 26275848.
"BAIAP2 is related to emotional modulation of human memory strength.". PLoS One. 2014. PMID 24392092.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] BAIAP2 - Cronfa NCBI

[1]

[2]