BCHE

BCHE
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1P0P, 4AXB, 4B0P, 2XQG, 1XLV, 2WIK, 2WIL, 1P0Q, 1XLU, 4BDS, 2XQF, 2PM8, 2XQK, 4AQD, 4BBZ, 2WID, 2XMB, 1XLW, 2XMC, 4TPK, 2XMG, 2XMD, 3DKK, 3O9M, 2WSL, 2WIJ, 1P0I, 2WIG, 2XQJ, 3DJY, 1P0M, 4B0O, 2XQI, 2Y1K, 4XII, 2WIF, 2J4C
Dynodwyr
Cyfenwau	BCHE, CHE1, CHE2, E1, butyrylcholinesterase, BCHED
Dynodwyr allanol	OMIM: 177400 HomoloGene: 20065 GeneCards: BCHE
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0004091 carboxylic ester hydrolase activity; • amyloid-beta binding; • cholinesterase activity; • choline binding; • catalytic activity; • identical protein binding; • acetylcholinesterase activity; • enzyme binding; • hydrolase activity; • hydrolase activity, acting on ester bonds;
Cydrannau o'r gell	• endoplasmic reticulum lumen; • blood microparticle; • bilen; • extracellular region; • Reticwlwm endoplasmig; • nuclear envelope lumen; • extracellular space;
Prosesau biolegol	• choline metabolic process; • response to nutrient; • neuroblast differentiation; • response to glucocorticoid; • negative regulation of synaptic transmission; • learning; • proses metabolig cocên; • response to alkaloid; • response to folic acid; • negative regulation of cell population proliferation;
	Sources:Amigo / QuickGO
Orthologau
	590
	n/a
	ENSG00000114200
	n/a
	P06276
	n/a
	NM_000055
	n/a
	NP_000046
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BCHE yw BCHE a elwir hefyd yn Butyrylcholinesterase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q26.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BCHE.

E1
CHE1
CHE2

Llyfryddiaeth

"Human butyrylcholinesterase efficacy against nerve agent exposure. ". J Biochem Mol Toxicol. 2017. PMID 28225154.
"Low Serum-Butyrylcholinesterase Activity as a Prognostic Marker of Mortality Associates with Poor Cardiac Function in Acute Myocardial Infarction. ". Clin Lab. 2016. PMID 27468571.
"Activity and polymorphisms of butyrylcholinesterase in a Polish population. ". Chem Biol Interact. 2016. PMID 27109752.
"Butyrylcholinesterase expression is regulated by fatty acids in HepG2 cells. ". Chem Biol Interact. 2016. PMID 27106529.
"Understanding the non-catalytic behavior of human butyrylcholinesterase silent variants: Comparison of wild-type enzyme, catalytically active Ala328Cys mutant, and silent Ala328Asp variant.". Chem Biol Interact. 2016. PMID 27062896.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] BCHE - Cronfa NCBI

[1]

[2]