BUB3

BUB3
Dynodwyr
Cyfenwau	BUB3, BUB3L, hmitotic checkpoint protein, BUB3 mitotic checkpoint protein
Dynodwyr allanol	OMIM: 603719 HomoloGene: 3470 GeneCards: BUB3
Patrwm RNA pattern
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	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • ubiquitin binding;
Cydrannau o'r gell	• cytosol; • Cromosom; • nucleoplasm; • chromosome, centromeric region; • cnewyllyn cell; • kinetochore; • mitotic checkpoint complex; • bub1-bub3 complex;
Prosesau biolegol	• chromosome segregation; • Cellraniad; • regulation of chromosome segregation; • GO:0007126 Meiosis; • mitotic sister chromatid segregation; • cell cycle; • anaphase-promoting complex-dependent catabolic process; • attachment of spindle microtubules to kinetochore; • mitotic spindle assembly checkpoint signaling; • protein localization to kinetochore; • regulation of mitotic cell cycle phase transition; • ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologau
	9184
	n/a
	ENSG00000154473
	n/a
	O43684
	n/a
	NM_004725; NM_001007793
	n/a
	NP_001007794; NP_004716
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BUB3 yw BUB3 a elwir hefyd yn BUB3, mitotic checkpoint protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10q26.13.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BUB3.

BUB3L
hBUB3

Llyfryddiaeth

"Assignment of BUB3 to human chromosome band 10q26 by in situ hybridization. ". Cytogenet Cell Genet. 2000. PMID 10828586.
"Functional and Structural Characterization of Bub3Â·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells. ". J Biol Chem. 2016. PMID 27030009.
"Co-silencing of human Bub3 and dynein highlights an antagonistic relationship in regulating kinetochore-microtubule attachments. ". FEBS Lett. 2015. PMID 26526612.
"A motif from Lys216 to Lys222 in human BUB3 protein is a nuclear localization signal and critical for BUB3 function in mitotic checkpoint. ". J Biol Chem. 2015. PMID 25814666.
"Molecular cloning and characterization of the human budding uninhibited by benomyl (BUB3) promoter.". Gene. 2002. PMID 12242018.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] BUB3 - Cronfa NCBI

[1]

[2]