CACNB4

CACNB4
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2D46
Dynodwyr
Cyfenwau	CACNB4, CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6, calcium voltage-gated channel auxiliary subunit beta 4
Dynodwyr allanol	OMIM: 601949 HomoloGene: 20188 GeneCards: CACNB4
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• voltage-gated calcium channel activity; • voltage-gated ion channel activity; • GO:0001948, GO:0016582 protein binding; • calcium channel activity; • high voltage-gated calcium channel activity;
Cydrannau o'r gell	• voltage-gated calcium channel complex; • cytosol; • Cellbilen; • synapse; • cytoplasmic side of plasma membrane;
Prosesau biolegol	• regulation of voltage-gated calcium channel activity; • regulation of ion transmembrane transport; • membrane depolarization; • cludo ïon; • calcium ion transport; • chemical synaptic transmission; • neuromuscular junction development; • calcium ion transmembrane transport; • cardiac conduction;
	Sources:Amigo / QuickGO
Orthologau
	785
	n/a
	ENSG00000182389
	n/a
	O00305
	n/a
NM_000726; NM_001005746; NM_001005747; NM_001145798; NM_001320722;
	NM_001330113; NM_001330114; NM_001330115; NM_001330116; NM_001330117; NM_001330118
	n/a
NP_000717; NP_001005746; NP_001005747; NP_001139270; NP_001307651;
	NP_001317042; NP_001317043; NP_001317044; NP_001317045; NP_001317046; NP_001317047
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CACNB4 yw CACNB4 a elwir hefyd yn Calcium voltage-gated channel auxiliary subunit beta 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q23.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CACNB4.

EA5
EJM
CAB4
EIG9
EJM4
EJM6
CACNLB4

Llyfryddiaeth

"[Physiological role of presynaptic Ca2+ channel complexes on neurotransmitter release]. ". Seikagaku. 2008. PMID 18712068.
"The GK domain of the voltage-dependent calcium channel beta subunit is essential for binding to the alpha subunit. ". Biochem Biophys Res Commun. 2007. PMID 17618603.
"Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4. ". Headache. 2006. PMID 16866717.
"Solution structure of the N-terminal A domain of the human voltage-gated Ca2+channel beta4a subunit. ". Protein Sci. 2006. PMID 16385006.
"Towards a unified nomenclature describing voltage-gated calcium channel genes.". Hum Genet. 1997. PMID 9254840.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CACNB4 - Cronfa NCBI

[1]

[2]