CANT1

CANT1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1S18, 1S1D, 2H2N, 2H2U
Dynodwyr
Cyfenwau	CANT1, DBQD, SCAN-1, SCAN1, SHAPY, DBQD1, calcium activated nucleotidase 1, EDM7
Dynodwyr allanol	OMIM: 613165 HomoloGene: 69460 GeneCards: CANT1
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• uridine-diphosphatase activity; • hydrolase activity; • signal transducer activity; • nucleoside-diphosphatase activity; • metal ion binding; • calcium ion binding; • protein homodimerization activity; • adenosine-diphosphatase activity; • guanosine-diphosphatase activity; • GO:0097382 pyrophosphatase activity;
Cydrannau o'r gell	• integral component of membrane; • Golgi cisterna membrane; • Golgi apparatus; • extracellular exosome; • endoplasmic reticulum membrane; • Reticwlwm endoplasmig; • extracellular region; • Cellbilen; • bilen; • specific granule lumen; • tertiary granule lumen; • ficolin-1-rich granule lumen;
Prosesau biolegol	• positive regulation of I-kappaB kinase/NF-kappaB signaling; • proteoglycan biosynthetic process; • GO:0072468 signal transduction; • neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologau
	124583
	n/a
	ENSG00000171302
	n/a
	Q8WVQ1
	n/a
	NM_001159772; NM_001159773; NM_138793
	n/a
	NP_001153244; NP_001153245; NP_620148
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CANT1 yw CANT1 a elwir hefyd yn Soluble calcium-activated nucleotidase 1 a Calcium activated nucleotidase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CANT1.

DBQD
EDM7
DBQD1
SCAN1
SHAPY
SCAN-1

Llyfryddiaeth

"The androgen-regulated Calcium-Activated Nucleotidase 1 (CANT1) is commonly overexpressed in prostate cancer and is tumor-biologically relevant in vitro. ". Am J Pathol. 2011. PMID 21435463.
"A founder mutation of CANT1 common in Korean and Japanese Desbuquois dysplasia. ". J Hum Genet. 2011. PMID 21412251.
"MED resulting from recessively inherited mutations in the gene encoding calcium-activated nucleotidase CANT1. ". Am J Med Genet A. 2017. PMID 28742282.
"A novel CANT1 mutation in three Indian patients with Desbuquois dysplasia Kim type. ". Eur J Med Genet. 2015. PMID 25486376.
"Desbuquois dysplasia type I and fetal hydrops due to novel mutations in the CANT1 gene.". Eur J Hum Genet. 2011. PMID 21654728.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CANT1 - Cronfa NCBI

[1]

[2]