CD59 |
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Dynodwyr |
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Cyfenwau | CD59, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, CD59 molecule, CD59 molecule (CD59 blood group) |
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Dynodwyr allanol | OMIM: 107271 HomoloGene: 56386 GeneCards: CD59 |
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Orthologau |
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Species | Bod dynol | Llygoden |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lleoliad (UCSC) | n/a | n/a |
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PubMed search | [1] | n/a |
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Wicidata |
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Protein sy'n cael ei godio yn y corff dynol gan y genyn CD59 yw CD59 a elwir hefyd yn CD59 antigen, complement regulatory protein, isoform CRA_b (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p13.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CD59.
- 1F5
- EJ16
- EJ30
- EL32
- G344
- MIN1
- MIN2
- MIN3
- MIRL
- HRF20
- MACIF
- MEM43
- MIC11
- MSK21
- 16.3A5
- HRF-20
- MAC-IP
- p18-20
- "A distinctive histidine residue is essential for in vivo glycation-inactivation of human CD59 transgenically expressed in mice erythrocytes: Implications for human diabetes complications. ". Am J Hematol. 2017. PMID 28815695.
- "Demyelination, strokes, and eculizumab: Lessons from the congenital CD59 gene mutations. ". Mol Immunol. 2017. PMID 28622911.
- "Therapy with eculizumab for patients with CD59 p.Cys89Tyr mutation. ". Ann Neurol. 2016. PMID 27568864.
- "Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins. ". Structure. 2016. PMID 27499440.
- "CD59: A long-known complement inhibitor has advanced to a blood group system.". Immunohematology. 2015. PMID 27187193.