CDC25A

CDC25A
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1C25
Dynodwyr
Cyfenwau	CDC25A, CDC25A2, cell division cycle 25A
Dynodwyr allanol	OMIM: 116947 HomoloGene: 1355 GeneCards: CDC25A
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • protein tyrosine phosphatase activity; • hydrolase activity; • protein kinase binding; • phosphoprotein phosphatase activity; • chaperone binding;
Cydrannau o'r gell	• cytoplasm; • cytosol; • intracellular anatomical structure; • nucleoplasm; • cnewyllyn cell;
Prosesau biolegol	• regulation of cyclin-dependent protein serine/threonine kinase activity; • cellular response to UV; • GO:0016576 protein dephosphorylation; • regulation of cell cycle; • Cellraniad; • G2/M transition of mitotic cell cycle; • cell cycle; • response to radiation; • peptidyl-tyrosine dephosphorylation; • cell population proliferation; • protein deubiquitination; • positive regulation of cell cycle G2/M phase transition; • G1/S transition of mitotic cell cycle; • positive regulation of G2/M transition of mitotic cell cycle; • positive regulation of mitotic cell cycle; • positive regulation of G2/MI transition of meiotic cell cycle;
	Sources:Amigo / QuickGO
Orthologau
	993
	n/a
	ENSG00000164045
	n/a
	P30304
	n/a
	NM_001789; NM_201567
	n/a
	NP_001780; NP_963861
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDC25A yw CDC25A a elwir hefyd yn Cell division cycle 25A, isoform CRA_a a Cell division cycle 25a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p21.31.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDC25A.

CDC25A2

Llyfryddiaeth

"Accumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth. ". Cancer Lett. 2017. PMID 28951130.
"CyclinD-CDK4/6 complexes phosphorylate CDC25A and regulate its stability. ". Oncogene. 2017. PMID 28192398.
"Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry. ". Cell Cycle. 2016. PMID 27580187.
"Identification of key genes in hepatocellular carcinoma and validation of the candidate gene, cdc25a, using gene set enrichment analysis, meta-analysis and cross-species comparison. ". Mol Med Rep. 2016. PMID 26647881.
"CDC25A-inhibitory RE derivatives bind to pocket adjacent to the catalytic site.". Mol Biosyst. 2013. PMID 23467652.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CDC25A - Cronfa NCBI

[1]

[2]