CDH8

CDH8
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1ZXK, 2A62
Dynodwyr
Cyfenwau	CDH8, Nbla04261, cadherin 8
Dynodwyr allanol	OMIM: 603008 HomoloGene: 55604 GeneCards: CDH8
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• calcium ion binding; • metal ion binding; • identical protein binding; • cytoskeletal protein binding; • protein homodimerization activity; • cadherin binding;
Cydrannau o'r gell	• axon terminus; • integral component of membrane; • synaptic cleft; • bilen; • Cellbilen; • synaptic membrane; • glutamatergic synapse; • cell surface; • catenin complex;
Prosesau biolegol	• response to cold; • cell adhesion; • adherens junction organization; • synaptic transmission, glutamatergic; • homophilic cell adhesion via plasma membrane adhesion molecules; • chemical synaptic transmission; • GO:1904739 regulation of synapse organization; • cell-cell junction assembly; • calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; • cell-cell adhesion mediated by cadherin; • cell-cell adhesion; • GO:0000767 cell morphogenesis;
	Sources:Amigo / QuickGO
Orthologau
	1006
	n/a
	ENSG00000150394
	n/a
	P55286
	n/a
	NM_001796
	n/a
	NP_001787
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDH8 yw CDH8 a elwir hefyd yn Cadherin 8 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q21.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDH8.

Nbla04261

Llyfryddiaeth

"Prenatal ethanol exposure disrupts intraneocortical circuitry, cortical gene expression, and behavior in a mouse model of FASD. ". J Neurosci. 2013. PMID 24285895.
"Identification of candidate intergenic risk loci in autism spectrum disorder. ". BMC Genomics. 2013. PMID 23879678.
"Pemphigus vulgaris autoantibody profiling by proteomic technique. ". PLoS One. 2013. PMID 23505434.
"Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture. ". Am J Physiol Cell Physiol. 2011. PMID 21389276.
"Rare familial 16q21 microdeletions under a linkage peak implicate cadherin 8 (CDH8) in susceptibility to autism and learning disability.". J Med Genet. 2011. PMID 20972252.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CDH8 - Cronfa NCBI

[1]

[2]