CDON

CDON
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3D1M, 3N1F, 3N1Q
Dynodwyr
Cyfenwau	CDON, CDO, CDON1, HPE11, ORCAM, cell adhesion associated, oncogene regulated, Ihog
Dynodwyr allanol	OMIM: 608707 HomoloGene: 22996 GeneCards: CDON
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• integral component of membrane; • bilen; • GO:0005578 extracellular matrix; • Cellbilen; • integral component of plasma membrane; • collagen-containing extracellular matrix;
Prosesau biolegol	• regulation of neuron differentiation; • positive regulation of small GTPase mediated signal transduction; • positive regulation of protein phosphorylation; • regulation of protein heterodimerization activity; • positive regulation of skeletal muscle tissue development; • positive regulation of muscle cell differentiation; • embryonic body morphogenesis; • cell fate specification; • skeletal muscle satellite cell differentiation; • positive regulation of neural precursor cell proliferation; • lens development in camera-type eye; • positive regulation of myoblast differentiation; • embryonic morphogenesis; • positive regulation of neuron differentiation; • cerebral cortex development; • embryonic retina morphogenesis in camera-type eye; • smoothened signaling pathway; • striated muscle cell differentiation; • myoblast fusion; • anterior/posterior pattern specification; • positive regulation of MAPK cascade; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • cell adhesion;
	Sources:Amigo / QuickGO
Orthologau
	50937
	n/a
	ENSG00000064309
	n/a
	Q4KMG0
	n/a
	NM_001243597; NM_016952; NM_001378964
	n/a
	NP_001230526; NP_058648; NP_001365893
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDON yw CDON a elwir hefyd yn Cell adhesion molecule-related/down-regulated by oncogenes a Cell adhesion associated, oncogene regulated (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q24.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDON.

CDO
CDON1
HPE11
ORCAM

Llyfryddiaeth

"Identification of transmembrane protein in prostate cancer by the Escherichia coli ampicillin secretion trap: expression of CDON is involved in tumor cell growth and invasion. ". Pathobiology. 2011. PMID 21849809.
"Regulation by miR181 family of the dependence receptor CDON tumor suppressive activity in neuroblastoma. ". J Natl Cancer Inst. 2014. PMID 25313246.
"A Nonsense Mutation in the Hedgehog Receptor CDON Associated With Pituitary Stalk Interruption Syndrome. ". J Clin Endocrinol Metab. 2016. PMID 26529631.
"CDO, an Hh-coreceptor, mediates lung cancer cell proliferation and tumorigenicity through Hedgehog signaling. ". PLoS One. 2014. PMID 25369201.
"Cdon and Boc: Two transmembrane proteins implicated in cell-cell communication.". Int J Biochem Cell Biol. 2012. PMID 22326621.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CDON - Cronfa NCBI

[1]

[2]