CST3

CST3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1G96, 1R4C, 1TIJ, 3GAX, 3NX0, 3PS8, 3QRD, 3S67, 3SVA
Dynodwyr
Cyfenwau	CST3, ARMD11, HEL-S-2, cystatin C
Dynodwyr allanol	OMIM: 604312 HomoloGene: 78 GeneCards: CST3
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• peptidase inhibitor activity; • cysteine-type endopeptidase inhibitor activity; • amyloid-beta binding; • GO:0001948, GO:0016582 protein binding; • identical protein binding; • endopeptidase inhibitor activity; • protease binding;
Cydrannau o'r gell	• extracellular region; • extracellular exosome; • tertiary granule lumen; • ficolin-1-rich granule lumen; • basement membrane; • extracellular space; • cytoplasm; • lysosome; • multivesicular body; • Reticwlwm endoplasmig; • endoplasmic reticulum lumen; • axon; • nuclear membrane; • fesigl; • cell projection; • soma; • contractile fiber; • perinuclear region of cytoplasm; • Golgi apparatus; • Cellbilen;
Prosesau biolegol	• negative regulation of proteolysis; • defense response; • negative regulation of peptidase activity; • negative regulation of extracellular matrix disassembly; • regulation of tissue remodeling; • negative regulation of blood vessel remodeling; • negative regulation of elastin catabolic process; • negative regulation of collagen catabolic process; • neutrophil degranulation; • supramolecular fiber organization; • eye development; • response to hypoxia; • cell activation; • GO:0097285 apoptotic process; • GO:0001306 response to oxidative stress; • brain development; • salivary gland development; • embryo implantation; • positive regulation of cell population proliferation; • male gonad development; • response to toxic substance; • response to carbohydrate; • response to inorganic substance; • GO:1904578 response to organic cyclic compound; • response to nutrient levels; • response to estradiol; • cellular response to oxidative stress; • circadian sleep/wake cycle, REM sleep; • regulation of programmed cell death; • post-translational protein modification; • positive regulation of DNA replication; • response to axon injury; • Sertoli cell development; • negative regulation of cell death; • cellular response to hydrogen peroxide; • negative regulation of cysteine-type endopeptidase activity; • negative regulation of endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologau
	1471
	n/a
	ENSG00000101439
	n/a
	P01034
	n/a
	NM_001288614; NM_000099
	n/a
	NP_000090; NP_001275543
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CST3 yw CST3 a elwir hefyd yn Cystatin C (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20p11.21.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CST3.

ARMD11
HEL-S-2

Llyfryddiaeth

"Serum cystatin C is associated with subclinical atherosclerosis in patients with type 2 diabetes: A retrospective study. ". Diab Vasc Dis Res. 2018. PMID 29090609.
"Association of epicardial adipose tissue with serum level of cystatin C in type 2 diabetes. ". PLoS One. 2017. PMID 28922364.
"Preoperative serum cystatin-C as a potential biomarker for prognosis of renal cell carcinoma. ". PLoS One. 2017. PMID 28586363.
"Serum creatinine and cystatin C provide conflicting evidence of acute kidney injury following acute ingestion of potassium permanganate and oxalic acid. ". Clin Toxicol (Phila). 2017. PMID 28535124.
"Accuracy of cystatin C in prediction of acute kidney injury in children; serum or urine levels: which one works better? A systematic review and meta-analysis.". BMC Nephrol. 2017. PMID 28372557.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CST3 - Cronfa NCBI

[1]

[2]