CST5

CST5
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1RN7, 1ROA
Dynodwyr
Cyfenwau	CST5, cystatin D
Dynodwyr allanol	OMIM: 123858 HomoloGene: 55615 GeneCards: CST5
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• peptidase inhibitor activity; • GO:0001948, GO:0016582 protein binding; • cysteine-type endopeptidase inhibitor activity; • protease binding;
Cydrannau o'r gell	• extracellular region; • extracellular exosome; • extracellular space;
Prosesau biolegol	• negative regulation of peptidase activity; • negative regulation of cysteine-type endopeptidase activity; • negative regulation of endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologau
	1473
	n/a
	ENSG00000170367
	n/a
	P28325
	n/a
	NM_001900
	n/a
	NP_001891
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CST5 yw CST5 a elwir hefyd yn Cystatin D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20p11.21.^[2]

Llyfryddiaeth

"Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression. ". J Biol Chem. 2015. PMID 26364852.
"Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. ". J Clin Invest. 2009. PMID 19662683.
"Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile. ". J Biol Chem. 2005. PMID 15728581.
"A sequence variation in the human cystatin D gene resulting in an amino acid (Cys/Arg) polymorphism at the protein level. ". Hum Genet. 1993. PMID 8444475.
"Localization of the human cystatin D gene (CST5) to chromosome 20p11.21 by in situ hybridization.". Cytogenet Cell Genet. 1993. PMID 8422752.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CST5 - Cronfa NCBI

[1]

[2]