CSTF3

CSTF3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2OND, 2OOE
Dynodwyr
Cyfenwau	CSTF3, CSTF-77, cleavage stimulation factor subunit 3
Dynodwyr allanol	OMIM: 600367 HomoloGene: 1014 GeneCards: CSTF3
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • mRNA binding; • RNA binding;
Cydrannau o'r gell	• cnewyllyn cell; • nucleoplasm;
Prosesau biolegol	• mRNA splicing, via spliceosome; • termination of RNA polymerase II transcription; • mRNA polyadenylation; • mRNA cleavage; • GO:0033168, GO:0036404, GO:1902360 RNA processing; • mRNA processing; • mRNA 3'-end processing; • RNA 3'-end processing;
	Sources:Amigo / QuickGO
Orthologau
	1479
	n/a
	ENSG00000176102
	n/a
	Q12996
	n/a
	NM_001033505; NM_001033506; NM_001326
	n/a
	NP_001028677; NP_001028678; NP_001317
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CSTF3 yw CSTF3 a elwir hefyd yn Cleavage stimulation factor subunit 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p13.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSTF3.

CSTF-77

Llyfryddiaeth

"The conserved intronic cleavage and polyadenylation site of CstF-77 gene imparts control of 3' end processing activity through feedback autoregulation and by U1 snRNP. ". PLoS Genet. 2013. PMID 23874216.
"Interactions of CstF-64, CstF-77, and symplekin: implications on localisation and function. ". Mol Biol Cell. 2011. PMID 21119002.
"The hinge domain of the cleavage stimulation factor protein CstF-64 is essential for CstF-77 interaction, nuclear localization, and polyadenylation. ". J Biol Chem. 2010. PMID 19887456.
"Chimeric human CstF-77/Drosophila Suppressor of forked proteins rescue suppressor of forked mutant lethality and mRNA 3' end processing in Drosophila. ". Proc Natl Acad Sci U S A. 2002. PMID 12149458.
"A human polyadenylation factor is a G protein beta-subunit homologue.". J Biol Chem. 1992. PMID 1358884.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CSTF3 - Cronfa NCBI

[1]

[2]