CTSZ

CTSZ
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1DEU, 1EF7
Dynodwyr
Cyfenwau	CTSZ, CTSX, cathepsin Z
Dynodwyr allanol	OMIM: 603169 HomoloGene: 1022 GeneCards: CTSZ
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • GO:0070122 peptidase activity; • hydrolase activity; • cysteine-type endopeptidase activity; • cysteine-type peptidase activity; • carboxypeptidase activity;
Cydrannau o'r gell	• endoplasmic reticulum lumen; • COPII-coated ER to Golgi transport vesicle; • intracellular membrane-bounded organelle; • Reticwlwm endoplasmig; • Cellbilen; • endoplasmic reticulum-Golgi intermediate compartment membrane; • extracellular exosome; • Golgi membrane; • extracellular region; • specific granule lumen; • ficolin-1-rich granule lumen; • extracellular space; • lysosome; • cell surface; • growth cone; • GO:0016023 cytoplasmic vesicle; • cell cortex region; • collagen-containing extracellular matrix;
Prosesau biolegol	• proteolysis involved in cellular protein catabolic process; • COPII vesicle coating; • endoplasmic reticulum to Golgi vesicle-mediated transport; • epithelial tube branching involved in lung morphogenesis; • angiotensin maturation; • neutrophil degranulation; • proteolysis; • negative regulation of plasminogen activation; • negative regulation of neuron projection development; • negative regulation of protein binding; • positive regulation of neuron apoptotic process; • regulation of neuron death; • positive regulation of neural precursor cell proliferation;
	Sources:Amigo / QuickGO
Orthologau
	1522
	n/a
	ENSG00000101160
	n/a
	Q9UBR2
	n/a
	NM_001336
	n/a
	NP_001327
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTSZ yw CTSZ a elwir hefyd yn Cathepsin Z (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.32.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CTSZ.

CTSX

Llyfryddiaeth

"Characterization of cathepsin X in colorectal cancer development and progression. ". Pathol Res Pract. 2014. PMID 25442015.
"Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients. ". BMC Cancer. 2014. PMID 24725597.
"Cellular senescence induced by cathepsin X downregulation. ". Eur J Cell Biol. 2011. PMID 21616554.
"Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study. ". Hum Immunol. 2011. PMID 21354459.
"RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties.". J Biol Chem. 2006. PMID 17065156.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CTSZ - Cronfa NCBI

[1]

[2]