CUL7

CUL7
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2JNG
Dynodwyr
Cyfenwau	CUL7, 3M1, KIAA0076, dJ20C7.5, cullin 7, CUL-7
Dynodwyr allanol	OMIM: 609577 HomoloGene: 56683 GeneCards: CUL7
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • ubiquitin protein ligase binding;
Cydrannau o'r gell	• cytoplasm; • cytosol; • centrosome; • Golgi apparatus; • microtubule organizing center; • Cul7-RING ubiquitin ligase complex; • perinuclear region of cytoplasm; • anaphase-promoting complex; • 3M complex; • Cytosgerbwd;
Prosesau biolegol	• Golgi organization; • ubiquitin-dependent protein catabolic process; • placenta development; • mitotic cytokinesis; • proteolysis; • vasculogenesis; • IRE1-mediated unfolded protein response; • positive regulation of dendrite morphogenesis; • protein ubiquitination; • epithelial to mesenchymal transition; • GO:0022415 viral process; • microtubule cytoskeleton organization; • regulation of mitotic nuclear division; • post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologau
	9820
	n/a
	ENSG00000044090
	n/a
	Q14999
	n/a
	NM_001168370; NM_014780; NM_001374872; NM_001374873; NM_001374874
	n/a
	NP_001161842; NP_055595; NP_001361801; NP_001361802; NP_001361803
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CUL7 yw CUL7 a elwir hefyd yn Cullin 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CUL7.

3M1
CUL-7
KIAA0076
dJ20C7.5

Llyfryddiaeth

"Changes in facial appearance from neonate to adult in 3-M syndrome patient with novel CUL7 gene mutations. ". J Pediatr Endocrinol Metab. 2016. PMID 26488604.
"Cullin7 is required for lung cancer cell proliferation and is overexpressed in lung cancer. ". Oncol Res. 2015. PMID 25706399.
"Inhibition of Liver Carcinoma Cell Invasion and Metastasis by Knockdown of Cullin7 In Vitro and In Vivo. ". Oncol Res. 2016. PMID 27053346.
"High Expression of Cullin7 Correlates with Unfavorable Prognosis in Epithelial Ovarian Cancer Patients. ". Cancer Invest. 2016. PMID 26962950.
"Pre- and post-natal growth in two sisters with 3-M syndrome.". Eur J Med Genet. 2016. PMID 26850509.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CUL7 - Cronfa NCBI

[1]

[2]