CYGB

CYGB
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1UMO, 1URV, 1URY, 1UT0, 1UX9, 1V5H, 2DC3, 3AG0, 4B3W
Dynodwyr
Cyfenwau	CYGB, HGB, STAP, cytoglobin
Dynodwyr allanol	OMIM: 608759 HomoloGene: 12706 GeneCards: CYGB
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• fatty acid peroxidase activity; • metal ion binding; • heme binding; • peroxidase activity; • catalase activity; • nitric oxide dioxygenase activity; • oxygen binding; • oxygen carrier activity; • iron ion binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• cytoplasm; • cytosol; • neuron projection; • soma; • nuclear speck;
Prosesau biolegol	• response to hypoxia; • GO:0001306 response to oxidative stress; • negative regulation of hepatic stellate cell activation; • negative regulation of collagen biosynthetic process; • fatty acid oxidation; • regulation of nitric-oxide synthase activity; • negative regulation of fibroblast migration; • cellular oxidant detoxification; • oxygen transport;
	Sources:Amigo / QuickGO
Orthologau
	114757
	n/a
	ENSG00000161544
	n/a
	Q8WWM9
	n/a
	NM_134268
	n/a
	NP_599030
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYGB yw CYGB a elwir hefyd yn Cytoglobin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYGB.

HGB
STAP

Llyfryddiaeth

"Cytoglobin ligand binding regulated by changing haem-co-ordination in response to intramolecular disulfide bond formation and lipid interaction. ". Biochem J. 2015. PMID 25327890.
"Cytoglobin in tumor hypoxia: novel insights into cancer suppression. ". Tumour Biol. 2014. PMID 24816917.
"Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences. ". Biochim Biophys Acta. 2016. PMID 26928591.
"Cytoglobin as a Biomarker in Cancer: Potential Perspective for Diagnosis and Management. ". Biomed Res Int. 2015. PMID 26339645.
"Coupling of disulfide bond and distal histidine dissociation in human ferrous cytoglobin regulates ligand binding.". FEBS Lett. 2015. PMID 25601563.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CYGB - Cronfa NCBI

[1]

[2]