DCX

DCX
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	4ATU, 1MJD, 2BQQ, 2XRP, 5IN7, 5IOI, 5IKC, 5IP4, 5IO9
Dynodwyr
Cyfenwau	DCX, DBCN, DC, LISX, SCLH, XLIS, doublecortin
Dynodwyr allanol	OMIM: 300121 HomoloGene: 7683 GeneCards: DCX
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • protein kinase binding; • microtubule binding;
Cydrannau o'r gell	• cell projection; • microtubule associated complex; • microtubule; • Cytosgerbwd; • cytosol; • neuron projection; • cytoplasm; • GO:0035085 axoneme;
Prosesau biolegol	• cell differentiation; • nervous system development; • multicellular organism development; • central nervous system development; • neuron migration; • GO:0007243 intracellular signal transduction; • axoneme assembly; • photoreceptor cell development; • retina development in camera-type eye;
	Sources:Amigo / QuickGO
Orthologau
	1641
	n/a
	ENSG00000077279
	n/a
	O43602
	n/a
NM_000555; NM_001195553; NM_178151; NM_178152; NM_178153;
	NM_001369370; NM_001369371; NM_001369372; NM_001369373; NM_001369374
	n/a
NP_000546; NP_001182482; NP_835364; NP_835365; NP_835366;
	NP_001356299; NP_001356300; NP_001356301; NP_001356302; NP_001356303
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DCX yw DCX a elwir hefyd yn Doublecortin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xq23.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DCX.

DC
DBCN
LISX
SCLH
XLIS

Llyfryddiaeth

"Doublecortin Is Excluded from Growing Microtubule Ends and Recognizes the GDP-Microtubule Lattice. ". Curr Biol. 2016. PMID 27238282.
"Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies. ". J Biol Chem. 2016. PMID 27226599.
"Novel DCX mutation-caused lissencephaly in a boy and very mild heterotopia in his mother. ". Pediatr Int. 2015. PMID 25868952.
"A critical and previously unsuspected role for doublecortin at the neuromuscular junction in mouse and human. ". Neuromuscul Disord. 2015. PMID 25817838.
"Doublecortin recognizes the longitudinal curvature of the microtubule end and lattice.". Curr Biol. 2014. PMID 25283777.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] DCX - Cronfa NCBI

[1]

[2]