DLG2

DLG2
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2BYG, 2HE2
Dynodwyr
Cyfenwau	DLG2, PPP1R58, PSD-93, PSD93, chapsyn-110, discs large homolog 2, discs large MAGUK scaffold protein 2
Dynodwyr allanol	OMIM: 603583 HomoloGene: 1046 GeneCards: DLG2
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• guanylate kinase activity; • kinase binding; • GO:0001948, GO:0016582 protein binding; • ionotropic glutamate receptor binding; • structural constituent of postsynaptic density;
Cydrannau o'r gell	• postsynaptic membrane; • cell projection; • bilen; • GO:0097483, GO:0097481 postsynaptic density; • voltage-gated potassium channel complex; • Cellbilen; • synapse; • axon; • cell junction; • basolateral plasma membrane; • ionotropic glutamate receptor complex; • juxtaparanode region of axon; • cytosol; • neuromuscular junction; • neuron projection; • postsynaptic density membrane; • glutamatergic synapse; • axon cytoplasm;
Prosesau biolegol	• chemical synaptic transmission; • receptor localization to synapse; • negative regulation of phosphatase activity; • receptor clustering; • nervous system development; • establishment or maintenance of epithelial cell apical/basal polarity; • sensory perception of pain; • GDP metabolic process; • GMP metabolic process; • MAPK cascade; • cellular response to potassium ion; • cell-cell adhesion; • maintenance of postsynaptic density structure; • anterograde axonal protein transport; • retrograde axonal protein transport; • neurotransmitter receptor localization to postsynaptic specialization membrane; • regulation of NMDA receptor activity;
	Sources:Amigo / QuickGO
Orthologau
	1740
	n/a
	ENSG00000150672
	n/a
	Q15700
	n/a
NM_001142699; NM_001142700; NM_001142702; NM_001206769; NM_001300983;
	NM_001364; NM_001351274; NM_001351275; NM_001351276; NM_001377966; NM_001377967; NM_001377968; NM_001377970; NM_001377971; NM_001377972; NM_001377973; NM_001377974; NM_001377975; NM_001377976; NM_001377977; NM_001377978; NM_001377979; NM_001377980; NM_001377981; NM_001377982; NM_001377983; NM_175892
	n/a
NP_001136171; NP_001136172; NP_001136174; NP_001193698; NP_001287912;
	NP_001355; NP_001338203; NP_001338204; NP_001338205; NP_001364895; NP_001364896; NP_001364897; NP_001364899; NP_001364900; NP_001364901; NP_001364902; NP_001364903; NP_001364904; NP_001364905; NP_001364906; NP_001364907; NP_001364908; NP_001364909; NP_001364910; NP_001364911; NP_001364912
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DLG2 yw DLG2 a elwir hefyd yn Disks large homolog 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q14.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DLG2.

PSD93
PSD-93
PPP1R58
chapsyn-110

Llyfryddiaeth

"Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy. ". Acta Crystallogr D Biol Crystallogr. 2013. PMID 23519667.
"Structure of the first PDZ domain of human PSD-93. ". Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID 20054121.
"Evaluation of DLG2 as a positional candidate for disposition index in African-Americans from the IRAS Family Study. ". Diabetes Res Clin Pract. 2010. PMID 19931931.
"Differential expression of a new isoform of DLG2 in renal oncocytoma. ". BMC Cancer. 2006. PMID 16640776.
"Expression, regulation and role of the MAGUK protein SAP-97 in human atrial myocardium.". Cardiovasc Res. 2002. PMID 12445884.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] DLG2 - Cronfa NCBI

[1]

[2]