DPP4

DPP4
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1J2E, 1N1M, 1NU6, 1NU8, 1PFQ, 1R9M, 1R9N, 1RWQ, 1TK3, 1TKR, 1U8E, 1W1I, 1WCY, 1X70, 2AJL, 2BGN, 2BGR, 2BUB, 2FJP, 2G5P, 2G5T, 2G63, 2HHA, 2I03, 2I78, 2IIT, 2IIV, 2JID, 2OAG, 2OGZ, 2OLE, 2ONC, 2OPH, 2OQI, 2OQV, 2P8S, 2QJR, 2QKY, 2QOE, 2QT9, 2QTB, 2RGU, 2RIP, 3BJM, 3C43, 3C45, 3CCB, 3CCC, 3D4L, 3EIO, 3F8S, 3G0B, 3G0C, 3G0D, 3G0G, 3H0C, 3HAB, 3HAC, 3KWF, 3KWJ, 3NOX, 3O95, 3O9V, 3OC0, 3OPM, 3Q0T, 3Q8W, 3QBJ, 3SWW, 3SX4, 3VJK, 3VJL, 3VJM, 3W2T, 4A5S, 4DSA, 4DSZ, 4DTC, 4G1F, 4JH0, 4KR0, 4L72, 4LKO, 4J3J, 4N8D, 4N8E, 4PNZ, 4PV7, 4QZV, 3WQH, 5KBY, 5ISM, 5I7U
Dynodwyr
Cyfenwau	DPP4, ADABP, ADCP2, CD26, DPPIV, TP103, dipeptidyl peptidase 4
Dynodwyr allanol	OMIM: 102720 HomoloGene: 3279 GeneCards: DPP4
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• dipeptidyl-peptidase activity; • signaling receptor binding; • identical protein binding; • GO:0070122 peptidase activity; • hydrolase activity; • virus receptor activity; • protein homodimerization activity; • serine-type peptidase activity; • protease binding; • aminopeptidase activity; • GO:0001948, GO:0016582 protein binding; • serine-type endopeptidase activity;
Cydrannau o'r gell	• lamellipodium membrane; • extracellular exosome; • lysosomal membrane; • endocytic vesicle; • integral component of membrane; • cell projection; • cell junction; • lamellipodium; • apical plasma membrane; • bilen; • focal adhesion; • cell surface; • intercellular canaliculus; • membrane raft; • extracellular region; • Cellbilen;
Prosesau biolegol	• response to hypoxia; • T cell costimulation; • psychomotor behavior; • behavioral fear response; • negative regulation of extracellular matrix disassembly; • regulation of cell-cell adhesion mediated by integrin; • locomotory exploration behavior; • endothelial cell migration; • positive regulation of cell population proliferation; • T cell activation; • cell adhesion; • viral entry into host cell; • regulation of insulin secretion; • proteolysis;
	Sources:Amigo / QuickGO
Orthologau
	1803
	n/a
	ENSG00000197635
	n/a
	P27487
	n/a
	NM_001935
	n/a
	NP_001926; NP_001366533; NP_001366534; NP_001366535
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DPP4 yw DPP4 a elwir hefyd yn Dipeptidyl peptidase 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q24.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DPP4.

CD26
ADABP
ADCP2
DPPIV
TP103

Llyfryddiaeth

"Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. ". Biochem Biophys Res Commun. 2017. PMID 29061303.
"Identification of senescent cell surface targetable protein DPP4. ". Genes Dev. 2017. PMID 28877934.
"Elevated CD26 Expression by Skin Fibroblasts Distinguishes a Profibrotic Phenotype Involved in Scar Formation Compared to Gingival Fibroblasts. ". Am J Pathol. 2017. PMID 28641076.
"Association of plasma dipeptidyl peptidase-4 activity with non-alcoholic fatty liver disease in nondiabetic Chinese population. ". Metabolism. 2017. PMID 28637594.
"Dipeptidyl Peptidase IV as a Prognostic Marker and Therapeutic Target in Papillary Thyroid Carcinoma.". J Clin Endocrinol Metab. 2017. PMID 28575350.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] DPP4 - Cronfa NCBI

[1]

[2]