F10

F10
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1C5M, 1EZQ, 1F0R, 1F0S, 1FAX, 1FJS, 1G2L, 1G2M, 1HCG, 1IOE, 1IQE, 1IQF, 1IQG, 1IQH, 1IQI, 1IQJ, 1IQK, 1IQL, 1IQM, 1IQN, 1KSN, 1LPG, 1LPK, 1LPZ, 1LQD, 1MQ5, 1MQ6, 1NFU, 1NFW, 1NFX, 1NFY, 1P0S, 1V3X, 1WU1, 1XKA, 1XKB, 1Z6E, 2BMG, 2BOH, 2BOK, 2BQ6, 2BQ7, 2BQW, 2CJI, 2D1J, 2EI6, 2EI7, 2EI8, 2FZZ, 2G00, 2GD4, 2H9E, 2J2U, 2J34, 2J38, 2J4I, 2J94, 2J95, 2JKH, 2P16, 2P3F, 2P3T, 2P3U, 2P93, 2P94, 2P95, 2PHB, 2PR3, 2Q1J, 2RA0, 2UWL, 2UWO, 2UWP, 2VH0, 2VH6, 2VVC, 2VVU, 2VVV, 2VWL, 2VWM, 2VWN, 2VWO, 2W26, 2W3I, 2W3K, 2WYG, 2WYJ, 2XBV, 2XBW, 2XBX, 2XBY, 2XC0, 2XC4, 2XC5, 2Y5F, 2Y5G, 2Y5H, 2Y7X, 2Y7Z, 2Y80, 2Y81, 2Y82, 3CEN, 3CS7, 3ENS, 3FFG, 3HPT, 3IIT, 3K9X, 3KL6, 3Q3K, 3SW2, 3TK5, 3TK6, 4A7I, 3KQB, 3KQC, 3KQD, 3KQE, 3LIW, 3M36, 3M37, 4BTI, 4BTT, 4BTU, 4Y6D, 4Y71, 4Y76, 4Y79, 4Y7A, 4Y7B, 4ZHA, 4ZH8, 5K0H
Dynodwyr
Cyfenwau	F10, FX, FXA, coagulation factor X
Dynodwyr allanol	OMIM: 613872 HomoloGene: 30976 GeneCards: F10
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• calcium ion binding; • GO:0070122 peptidase activity; • GO:0001948, GO:0016582 protein binding; • serine-type peptidase activity; • serine-type endopeptidase activity; • phospholipid binding; • hydrolase activity;
Cydrannau o'r gell	• endoplasmic reticulum lumen; • intrinsic component of external side of plasma membrane; • Cellbilen; • extracellular region; • Golgi lumen; • extracellular space;
Prosesau biolegol	• hemostasis; • positive regulation of protein kinase B signaling; • positive regulation of cell migration; • blood coagulation; • proteolysis; • endoplasmic reticulum to Golgi vesicle-mediated transport; • blood coagulation, extrinsic pathway;
	Sources:Amigo / QuickGO
Orthologau
	2159
	n/a
	ENSG00000126218
	n/a
	P00742
	n/a
	NM_000504; NM_001312674; NM_001312675
	n/a
	NP_000495; NP_001299603; NP_001299604
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn F10 yw F10 a elwir hefyd yn Coagulation factor X (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 13, band 13q34.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F10.

FX
FXA

Llyfryddiaeth

"Rendering factor Xa zymogen-like as a therapeutic strategy to treat bleeding. ". Curr Opin Hematol. 2017. PMID 28692575.
"[Homozygous missense mutation p.Val298Met of F10 gene causing hereditary coagulation factor X deficiency in a Chinese pedigree]. ". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2016. PMID 27264807.
"Novel Anthranilamide-Based FXa Inhibitors: Drug Design, Synthesis and Biological Evaluation. ". Molecules. 2016. PMID 27089317.
"A family with factor X deficiency from Argentina: a compound heterozygosis because of the combination of a new mutation (Gln138Arg) with an already known one (Glu350Lys). ". Blood Coagul Fibrinolysis. 2016. PMID 27031279.
"Spectrum of factor X gene mutations in Iranian patients with congenital factor X deficiency.". Blood Coagul Fibrinolysis. 2016. PMID 26891460.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] F10 - Cronfa NCBI

[1]

[2]