F11R

F11R
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1NBQ, 3EOY, 3TSZ, 4ODB
Dynodwyr
Cyfenwau	F11R, F11r, 9130004G24, AA638916, ESTM33, JAM, JAM-1, JAM-A, Jcam, Jcam1, Ly106, CD321, JAM1, JAMA, KAT, PAM-1, F11 receptor
Dynodwyr allanol	OMIM: 605721 HomoloGene: 14255 GeneCards: F11R
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• PDZ domain binding; • virus receptor activity; • GO:0001948, GO:0016582 protein binding; • cadherin binding;
Cydrannau o'r gell	• integral component of membrane; • bilen; • cell-cell junction; • bicellular tight junction; • Cellbilen; • slit diaphragm; • extracellular exosome; • GO:0016023 cytoplasmic vesicle; • cell junction;
Prosesau biolegol	• regulation of actin cytoskeleton reorganization; • cell differentiation; • establishment of endothelial intestinal barrier; • epithelial cell differentiation; • actomyosin structure organization; • extracellular matrix organization; • regulation of membrane permeability; • GO:0032657 regulation of cytokine production; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • positive regulation of blood pressure; • cell adhesion; • GO:0034259 negative regulation of GTPase activity; • bicellular tight junction assembly; • viral entry into host cell; • intestinal absorption; • response to radiation; • inflammatory response; • GO:0022415 viral process; • transforming growth factor beta receptor signaling pathway; • leukocyte migration; • protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologau
	50848
	n/a
	ENSG00000158769
	n/a
	Q9Y624
	n/a
NM_016946; NM_144501; NM_144502; NM_144503; NM_144504;
	NM_001348091; NM_001382727; NM_001382730; NM_001382733; NM_001382734
	n/a
NP_058642; NP_001335020; NP_001369656; NP_001369659; NP_001369662;
	NP_001369663
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn F11R yw F11R a elwir hefyd yn F11 receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F11R.

JAM
KAT
JAM1
JAMA
JCAM
CD321
PAM-1

Llyfryddiaeth

"Junctional Adhesion Molecule-A in Head and Neck Squamous Cell Carcinoma. ". Adv Otorhinolaryngol. 2016. PMID 27115511.
"Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF. ". Mol Biol Cell. 2016. PMID 26985018.
"A novel immunotoxin reveals a new role for CD321 in endothelial cells. ". PLoS One. 2017. PMID 29028806.
"Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma. ". Cancer Sci. 2017. PMID 28837251.
"Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells.". MBio. 2017. PMID 28196955.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] F11R - Cronfa NCBI

[1]

[2]