FGF7

FGF7
Dynodwyr
Cyfenwau	FGF7, HBGF-7, KGF, fibroblast growth factor 7
Dynodwyr allanol	OMIM: 148180 HomoloGene: 7316 GeneCards: FGF7
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• heparin binding; • fibroblast growth factor receptor binding; • GO:0001948, GO:0016582 protein binding; • chemoattractant activity; • growth factor activity; • 1-phosphatidylinositol-3-kinase activity; • protein tyrosine kinase activity; • phosphatidylinositol-4,5-bisphosphate 3-kinase activity;
Cydrannau o'r gell	• Golgi apparatus; • extracellular region;
Prosesau biolegol	• actin cytoskeleton reorganization; • mesenchymal cell proliferation; • positive regulation of keratinocyte proliferation; • positive regulation of epithelial cell proliferation involved in lung morphogenesis; • secretion by lung epithelial cell involved in lung growth; • positive regulation of epithelial cell proliferation; • regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; • MAPK cascade; • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • fibroblast growth factor receptor signaling pathway; • positive regulation of keratinocyte migration; • protein localization to cell surface; • response to wounding; • positive regulation of cell population proliferation; • epidermis development; • positive regulation of peptidyl-tyrosine phosphorylation; • hair follicle morphogenesis; • positive chemotaxis; • positive regulation of cell division; • GO:0072468 signal transduction; • branching involved in salivary gland morphogenesis; • phosphatidylinositol phosphate biosynthetic process; • peptidyl-tyrosine phosphorylation; • phosphatidylinositol-3-phosphate biosynthetic process; • regulation of signaling receptor activity; • positive regulation of protein kinase B signaling;
	Sources:Amigo / QuickGO
Orthologau
	2252
	n/a
	ENSG00000140285
	n/a
	P21781
	n/a
	NM_002009
	n/a
	NP_002000
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FGF7 yw FGF7 a elwir hefyd yn Fibroblast growth factor 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q21.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FGF7.

KGF
HBGF-7

Llyfryddiaeth

"In silico enhancement of the stability and activity of keratinocyte growth factor. ". J Theor Biol. 2017. PMID 28093295.
"Role of Keratinocyte Growth Factor in the Differentiation of Sweat Gland-Like Cells From Human Umbilical Cord-Derived Mesenchymal Stem Cells. ". Stem Cells Transl Med. 2016. PMID 26574554.
"FGF7 Over Expression is an Independent Prognosticator in Patients with Urothelial Carcinoma of the Upper Urinary Tract and Bladder. ". J Urol. 2015. PMID 25623741.
"In vivo over-expression of KGF mimic human middle ear cholesteatoma. ". Eur Arch Otorhinolaryngol. 2015. PMID 25138153.
"Recombinant keratinocyte growth factor 1 in tobacco potentially promotes wound healing in diabetic rats.". Biomed Res Int. 2014. PMID 24783215.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] FGF7 - Cronfa NCBI

[1]

[2]