FGF9

FGF9
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1G82, 1IHK
Dynodwyr
Cyfenwau	FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3, fibroblast growth factor 9
Dynodwyr allanol	OMIM: 600921 HomoloGene: 1523 GeneCards: FGF9
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• heparin binding; • fibroblast growth factor receptor binding; • protein tyrosine kinase activity; • phosphatidylinositol-4,5-bisphosphate 3-kinase activity; • 1-phosphatidylinositol-3-kinase activity; • growth factor activity;
Cydrannau o'r gell	• cytoplasm; • extracellular region; • basement membrane; • extracellular exosome; • extracellular space;
Prosesau biolegol	• eye development; • positive regulation of vascular endothelial growth factor receptor signaling pathway; • cell differentiation; • male gonad development; • chondrocyte differentiation; • substantia nigra development; • protein import into nucleus; • positive regulation of smoothened signaling pathway; • regulation of timing of cell differentiation; • positive regulation of epithelial cell proliferation; • lung development; • positive regulation of canonical Wnt signaling pathway; • negative regulation of Wnt signaling pathway; • GO:1901227 negative regulation of transcription by RNA polymerase II; • male sex determination; • MAPK cascade; • embryonic skeletal system development; • multicellular organism development; • GO:1901313 positive regulation of gene expression; • positive regulation of activin receptor signaling pathway; • positive regulation of cardiac muscle cell proliferation; • positive regulation of mesenchymal cell proliferation; • embryonic limb morphogenesis; • inner ear morphogenesis; • angiogenesis; • osteoblast differentiation; • positive regulation of cell population proliferation; • lung-associated mesenchyme development; • embryonic digestive tract development; • positive regulation of cell division; • GO:0072468 signal transduction; • positive regulation of MAPK cascade; • phosphatidylinositol phosphate biosynthetic process; • fibroblast growth factor receptor signaling pathway; • cell-cell signaling; • phosphatidylinositol-3-phosphate biosynthetic process; • peptidyl-tyrosine phosphorylation; • regulation of signaling receptor activity; • positive regulation of protein kinase B signaling; • regulation of molecular function; • positive regulation of vascular associated smooth muscle cell proliferation; • positive regulation of vascular associated smooth muscle cell migration; • negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching;
	Sources:Amigo / QuickGO
Orthologau
	2254
	n/a
	ENSG00000102678
	n/a
	P31371
	n/a
	NM_002010
	n/a
	NP_002001
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FGF9 yw FGF9 a elwir hefyd yn Fibroblast growth factor 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 13, band 13q12.11.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FGF9.

GAF
FGF-9
SYNS3
HBFG-9
HBGF-9

Llyfryddiaeth

"The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer. ". Oncotarget. 2016. PMID 27166269.
"Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases. ". J Biol Chem. 2015. PMID 26183774.
"FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells. ". BMC Cancer. 2015. PMID 25925261.
"Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. ". Nucleic Acids Res. 2014. PMID 24334956.
"Expression of fibroblast growth factor 9 is associated with poor prognosis in patients with resected non-small cell lung cancer.". Lung Cancer. 2014. PMID 24239165.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] FGF9 - Cronfa NCBI

[1]

[2]