HBP1 |
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Dynodwyr |
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Cyfenwau | HBP1, HMG-box transcription factor 1 |
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Dynodwyr allanol | OMIM: 616714 HomoloGene: 8171 GeneCards: HBP1 |
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Ontoleg y genyn |
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Gweithrediad moleciwlaidd | • DNA binding • GO:0001948, GO:0016582 protein binding • RNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
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Cydrannau o'r gell | • cnewyllyn cell • nucleoplasm • nuclear speck
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Prosesau biolegol | • GO:0009373 regulation of transcription, DNA-templated • Wnt signaling pathway • transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
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Sources:Amigo / QuickGO |
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Orthologau |
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Species | Bod dynol | Llygoden |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lleoliad (UCSC) | n/a | n/a |
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PubMed search | [1] | n/a |
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Wicidata |
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Protein sy'n cael ei godio yn y corff dynol gan y genyn HBP1 yw HBP1 a elwir hefyd yn HMG box-containing protein 1 a HMG-box transcription factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q22.3.[2]
- "Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells. ". Leukemia. 2005. PMID 16179914.
- "Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression. ". Mol Cell Biol. 2000. PMID 10958660.
- "Transcription Factor HBP1 Enhances Radiosensitivity by Inducing Apoptosis in Prostate Cancer Cell Lines. ". Anal Cell Pathol (Amst). 2016. PMID 26942107.
- "Hbp1 regulates the timing of neuronal differentiation during cortical development by controlling cell cycle progression. ". Development. 2015. PMID 26041766.
- "Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.". Cancer Res. 2007. PMID 17616670.