HOXB7

HOXB7
Dynodwyr
Cyfenwau	HOXB7, HHO.C1, HOX2, HOX2C, Hox-2.3, homeobox B7
Dynodwyr allanol	OMIM: 142962 HomoloGene: 55828 GeneCards: HOXB7
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • sequence-specific DNA binding; • DNA binding; • GO:0001948, GO:0016582 protein binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;
Cydrannau o'r gell	• cnewyllyn cell; • nucleoplasm; • cytosol; • nuclear body;
Prosesau biolegol	• multicellular organism development; • embryonic skeletal system morphogenesis; • myeloid cell differentiation; • positive regulation of branching involved in ureteric bud morphogenesis; • GO:0009373 regulation of transcription, DNA-templated; • transcription, DNA-templated; • anterior/posterior pattern specification; • transcription by RNA polymerase II; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologau
	3217
	n/a
	ENSG00000260027
	n/a
	P09629
	n/a
	NM_004502
	n/a
	NP_004493
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HOXB7 yw HOXB7 a elwir hefyd yn Homeobox B7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q21.32.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOXB7.

HOX2
HOX2C
HHO.C1
Hox-2.3

Llyfryddiaeth

"HOXB7 Expression is a Novel Biomarker for Long-term Prognosis After Resection of Hepatocellular Carcinoma. ". Anticancer Res. 2016. PMID 27272787.
"The roles of HOXB7 in promoting migration, invasion, and anti-apoptosis in gastric cancer. ". J Gastroenterol Hepatol. 2016. PMID 26968988.
"Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics. ". Tumour Biol. 2016. PMID 26307396.
"HOXB7-S3 inhibits the proliferation and invasion of MCF-7 human breast cancer cells. ". Mol Med Rep. 2015. PMID 26135503.
"Identification of several potential chromatin binding sites of HOXB7 and its downstream target genes in breast cancer.". Int J Cancer. 2015. PMID 26014856.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] HOXB7 - Cronfa NCBI

[1]

[2]