HSPA1L

HSPA1L
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3GDQ
Dynodwyr
Cyfenwau	HSPA1L, HSP70-1L, HSP70-HOM, HSP70T, hum70t, heat shock protein family A (Hsp70) member 1 like
Dynodwyr allanol	OMIM: 140559 HomoloGene: 135835 GeneCards: HSPA1L
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• unfolded protein binding; • nucleotide binding; • GO:0001948, GO:0016582 protein binding; • ATP binding; • heat shock protein binding; • ubiquitin protein ligase binding; • ATPase activity; • protein folding chaperone activity; • misfolded protein binding;
Cydrannau o'r gell	• COP9 signalosome; • cytosol; • mitochondrial matrix; • blood microparticle; • mitocondria; • nucleoplasm; • zona pellucida receptor complex; • cell body; • cytoplasm;
Prosesau biolegol	• regulation of cellular response to heat; • response to unfolded protein; • protein refolding; • positive regulation of protein targeting to mitochondrion; • binding of sperm to zona pellucida; • cellular response to heat; • Unfolded Protein Response; • chaperone cofactor-dependent protein refolding;
	Sources:Amigo / QuickGO
Orthologau
	3305
	n/a
ENSG00000234258; ENSG00000226704; ENSG00000236251; ENSG00000204390; ENSG00000206383;
	n/a
	n/a
	P34931
	n/a
	NM_005527
	n/a
	NP_005518
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HSPA1L yw HSPA1L a elwir hefyd yn Heat shock protein family A (Hsp70) member 1 like (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.33.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HSPA1L.

HSP70T
hum70t
HSP70-1L
HSP70-HOM

Llyfryddiaeth

"De novo and rare mutations in the HSPA1L heat shock gene associated with inflammatory bowel disease. ". Genome Med. 2017. PMID 28126021.
"Elevated level of HSPA1L mRNA correlates with graft-versus-host disease. ". Transpl Immunol. 2015. PMID 25680846.
"HSP70-hom gene polymorphisms modify the association of diethylhexyl phthalates with insulin resistance. ". Environ Mol Mutagen. 2014. PMID 25044062.
"Association of HSP70-hom genetic variant with prostate cancer risk. ". Mol Biol Rep. 2008. PMID 17578680.
"HSP70-hom gene polymorphism as a prognostic marker of graft-versus-host disease.". Transplantation. 2006. PMID 17060867.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] HSPA1L - Cronfa NCBI

[1]

[2]