IGF2BP2

IGF2BP2
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2CQH
Dynodwyr
Cyfenwau	IGF2BP2, IMP-2, IMP2, VICKZ2, insulin like growth factor 2 mRNA binding protein 2
Dynodwyr allanol	OMIM: 608289 HomoloGene: 4774 GeneCards: IGF2BP2
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• mRNA 5'-UTR binding; • GO:0001948, GO:0016582 protein binding; • mRNA binding; • translation regulator activity; • mRNA 3'-UTR binding; • nucleic acid binding; • RNA binding;
Cydrannau o'r gell	• cytoplasm; • Cytosgerbwd; • cnewyllyn cell; • cytosol;
Prosesau biolegol	• anatomical structure morphogenesis; • negative regulation of translation; • mRNA transport; • regulation of translation; • regulation of mRNA stability; • GO:0015915 transport;
	Sources:Amigo / QuickGO
Orthologau
	10644
	n/a
	ENSG00000073792
	n/a
	Q9Y6M1
	n/a
NM_001007225; NM_001291869; NM_001291872; NM_001291873; NM_001291874;
	NM_001291875; NM_006548
	n/a
NP_001007226; NP_001278798; NP_001278801; NP_001278802; NP_001278803;
	NP_001278804; NP_006539
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IGF2BP2 yw IGF2BP2 a elwir hefyd yn Insulin like growth factor 2 mRNA binding protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q27.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IGF2BP2.

IMP2
IMP-2
VICKZ2

Llyfryddiaeth

"Autoimmune Response to IGF2 mRNA-Binding Protein 2 (IMP2/p62) in Breast Cancer. ". Scand J Immunol. 2015. PMID 25721883.
"Correlation between IGF2BP2 gene polymorphism and the risk of breast cancer in Chinese Han women. ". Biomed Pharmacother. 2015. PMID 25661373.
"Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations. ". Diabetes. 2016. PMID 27625022.
"Association between IGF2BP2 Polymorphisms and Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis. ". Int J Environ Res Public Health. 2016. PMID 27294943.
"p62/IMP2 stimulates cell migration and reduces cell adhesion in breast cancer.". Oncotarget. 2015. PMID 26416451.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] IGF2BP2 - Cronfa NCBI

[1]

[2]