IGF2BP3

IGF2BP3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2E44
Dynodwyr
Cyfenwau	IGF2BP3, CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3, insulin like growth factor 2 mRNA binding protein 3
Dynodwyr allanol	OMIM: 608259 HomoloGene: 4773 GeneCards: IGF2BP3
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• mRNA 5'-UTR binding; • GO:0001948, GO:0016582 protein binding; • translation regulator activity; • mRNA 3'-UTR binding; • nucleic acid binding; • RNA binding;
Cydrannau o'r gell	• cnewyllyn cell; • cytoplasm; • cytosol;
Prosesau biolegol	• anatomical structure morphogenesis; • negative regulation of translation; • mRNA transport; • protein biosynthesis; • regulation of translation; • regulation of mRNA stability; • GO:0015915 transport;
	Sources:Amigo / QuickGO
Orthologau
	10643
	n/a
	ENSG00000136231
	n/a
	O00425
	n/a
	NM_006547
	n/a
	NP_006538
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IGF2BP3 yw IGF2BP3 a elwir hefyd yn Insulin like growth factor 2 mRNA binding protein 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p15.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IGF2BP3.

KOC
CT98
IMP3
KOC1
IMP-3
VICKZ3

Llyfryddiaeth

"Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is a marker that predicts presence of invasion in papillary biliary tumors. ". Hum Pathol. 2017. PMID 28089541.
"IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC. ". Cell Rep. 2016. PMID 27210763.
"Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition. ". J Clin Invest. 2017. PMID 28481226.
"Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non-small cell lung cancer. ". Tumour Biol. 2017. PMID 28381175.
"IMP3 Expression in Borderline Tumors of the Ovary.". Anticancer Res. 2017. PMID 28179304.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] IGF2BP3 - Cronfa NCBI

[1]

[2]