IL13RA1

IL13RA1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3BPN, 3BPO, 4HWB, 5E4E
Dynodwyr
Cyfenwau	IL13RA1, CD213A1, IL-13Ra, NR4, CT19, interleukin 13 receptor subunit alpha 1
Dynodwyr allanol	OMIM: 300119 HomoloGene: 1198 GeneCards: IL13RA1
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0016518 cytokine receptor activity; • GO:0001948, GO:0016582 protein binding; • interleukin-13 receptor activity; • GO:0019974 cytokine binding;
Cydrannau o'r gell	• integral component of membrane; • interleukin-13 receptor complex; • Cellbilen; • bilen; • external side of plasma membrane; • receptor complex;
Prosesau biolegol	• cell surface receptor signaling pathway; • cytokine-mediated signaling pathway; • interleukin-13-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologau
	3597
	n/a
	ENSG00000131724
	n/a
	P78552
	n/a
	NM_001560
	n/a
	NP_001551
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL13RA1 yw IL13RA1 a elwir hefyd yn Interleukin 13 receptor subunit alpha 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq24.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL13RA1.

NR4
CT19
CD213A1
IL-13Ra

Llyfryddiaeth

"The Interleukin-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4. ". J Innate Immun. 2015. PMID 25766112.
"Identification of single-nucleotide and repeat polymorphisms in two candidate genes, interleukin 4 receptor (IL4RA) and signal transducer and activator of transcription protein 6 (STAT6), for Th2-mediated diseases. ". J Hum Genet. 2002. PMID 12522691.
"Kinetic analysis of the interleukin-13 receptor complex. ". J Biol Chem. 2002. PMID 12354755.
"Mutation and functional analysis of IL-13 receptors in human malignant glioma cells. ". Oncol Res. 2001. PMID 11939409.
"Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor alpha chain 1: redundancy of requirement of tyrosine residue for STAT3 activation.". Int Immunol. 2000. PMID 11058569.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] IL13RA1 - Cronfa NCBI

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[2]