KCNA3

KCNA3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	4BGC
Dynodwyr
Cyfenwau	KCNA3, HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3, potassium voltage-gated channel subfamily A member 3
Dynodwyr allanol	OMIM: 176263 HomoloGene: 128570 GeneCards: KCNA3
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• outward rectifier potassium channel activity; • potassium channel activity; • voltage-gated ion channel activity; • ion channel activity; • voltage-gated potassium channel activity; • delayed rectifier potassium channel activity; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• bilen; • voltage-gated potassium channel complex; • Cellbilen; • integral component of plasma membrane; • axon; • membrane raft; • integral component of membrane; • calyx of Held; • glutamatergic synapse; • integral component of postsynaptic membrane; • integral component of presynaptic membrane;
Prosesau biolegol	• regulation of ion transmembrane transport; • cludo ïon; • potassium ion transport; • transmembrane transport; • protein homooligomerization; • potassium ion transmembrane transport; • potassium ion export across plasma membrane;
	Sources:Amigo / QuickGO
Orthologau
	3738
	n/a
	ENSG00000177272
	n/a
	P22001
	n/a
	NM_002232
	n/a
	NP_002223
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNA3 yw KCNA3 a elwir hefyd yn Potassium voltage-gated channel subfamily A member 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p13.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KCNA3.

MK3
HGK5
HLK3
PCN3
HPCN3
KV1.3
HUKIII

Llyfryddiaeth

"Molecular Determinants of Kv1.3 Potassium Channels-induced Proliferation. ". J Biol Chem. 2016. PMID 26655221.
"The voltage-gated potassium channel Kv1.3 is a promising multitherapeutic target against human pathologies. ". Expert Opin Ther Targets. 2016. PMID 26634786.
"Biophysical characterization and expression analysis of Kv1.3 potassium channel in primary human leukemic B cells. ". Cell Physiol Biochem. 2015. PMID 26393354.
"Human α-defensins are immune-related Kv1.3 channel inhibitors: new support for their roles in adaptive immunity. ". FASEB J. 2015. PMID 26148969.
"Inhibition of Kv1.3 Channels in Human Jurkat T Cells by Xanthohumol and Isoxanthohumol.". J Membr Biol. 2015. PMID 25688010.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] KCNA3 - Cronfa NCBI

[1]

[2]