KLK7

KLK7
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2QXG, 2QXH, 2QXI, 2QXJ, 3BSQ
Dynodwyr
Cyfenwau	KLK7, PRSS6, SCCE, hK7, kallikrein related peptidase 7
Dynodwyr allanol	OMIM: 604438 HomoloGene: 37998 GeneCards: KLK7
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0070122 peptidase activity; • serine-type peptidase activity; • hydrolase activity; • serine-type endopeptidase activity; • metalloendopeptidase activity;
Cydrannau o'r gell	• extracellular region; • epidermal lamellar body; • extracellular space; • secretory granule;
Prosesau biolegol	• positive regulation of antibacterial peptide production; • extracellular matrix disassembly; • proteolysis; • epidermis development;
	Sources:Amigo / QuickGO
Orthologau
	5650
	n/a
	ENSG00000169035
	n/a
	P49862; Q6DTY1
	n/a
	NM_139277; NM_001207053; NM_001243126; NM_005046
	n/a
	NP_001193982; NP_001230055; NP_005037; NP_644806
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KLK7 yw KLK7 a elwir hefyd yn Kallikrein 7 splice variant 3 a Kallikrein related peptidase 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.41.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KLK7.

hK7
SCCE
PRSS6

Llyfryddiaeth

"Specificity studies on Kallikrein-related peptidase 7 (KLK7) and effects of osmolytes and glycosaminoglycans on its peptidase activity. ". Biochim Biophys Acta. 2015. PMID 25448018.
"Serum human kallikrein 7 represents a new marker for cervical cancer. ". Med Oncol. 2014. PMID 25182706.
"Skin Barrier Function Is Not Impaired and Kallikrein 7 Gene Polymorphism Is Frequently Observed in Korean X-linked Ichthyosis Patients Diagnosed by Fluorescence in Situ Hybridization and Array Comparative Genomic Hybridization. ". J Korean Med Sci. 2016. PMID 27478344.
"Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells. ". Biol Chem. 2016. PMID 27279059.
"Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics.". J Biol Chem. 2015. PMID 26032414.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] KLK7 - Cronfa NCBI

[1]

[2]