LIN7C

LIN7C
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3LRA
Dynodwyr
Cyfenwau	LIN7C, LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3, lin-7 homolog C, crumbs cell polarity complex component
Dynodwyr allanol	OMIM: 612332 HomoloGene: 22649 GeneCards: LIN7C
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• protein domain specific binding; • cytoskeletal protein binding; • L27 domain binding; • PDZ domain binding;
Cydrannau o'r gell	• cytoplasm; • postsynaptic membrane; • GO:0097483, GO:0097481 postsynaptic density; • bilen; • cell-cell junction; • bicellular tight junction; • Cellbilen; • MPP7-DLG1-LIN7 complex; • cell junction; • basolateral plasma membrane; • neuron projection; • presynapse; • synapse; • glutamatergic synapse;
Prosesau biolegol	• protein localization to basolateral plasma membrane; • maintenance of epithelial cell apical/basal polarity; • protein transport; • morphogenesis of an epithelial sheet; • GO:0010554 neurotransmitter secretion; • exocytosis;
	Sources:Amigo / QuickGO
Orthologau
	55327
	n/a
	ENSG00000148943
	n/a
	Q9NUP9
	n/a
	NM_018362
	n/a
	NP_060832
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LIN7C yw LIN7C a elwir hefyd yn Lin-7 homolog C, crumbs cell polarity complex component (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p14.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LIN7C.

MALS3
VELI3
LIN-7C
MALS-3
LIN-7-C

Llyfryddiaeth

"The type III inositol 1,4,5-trisphosphate receptor preferentially transmits apoptotic Ca2+ signals into mitochondria. ". J Biol Chem. 2005. PMID 16192275.
"A general model for preferential hetero-oligomerization of LIN-2/7 domains: mechanism underlying directed assembly of supramolecular signaling complexes. ". J Biol Chem. 2005. PMID 16147993.
"Lin-7C/VELI3/MALS-3: an essential component in metastasis of human squamous cell carcinoma. ". Cancer Res. 2007. PMID 17942893.
"Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells. ". Sci Rep. 2014. PMID 24961284.
"Association study of theta EEG asymmetry and brain-derived neurotrophic factor gene variants in childhood-onset mood disorder.". Neuromolecular Med. 2008. PMID 18543122.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] LIN7C - Cronfa NCBI

[1]

[2]