LTBP1

LTBP1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1KSQ
Dynodwyr
Cyfenwau	LTBP1, latent transforming growth factor beta binding protein 1
Dynodwyr allanol	OMIM: 150390 HomoloGene: 522 GeneCards: LTBP1
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • calcium ion binding; • transforming growth factor beta-activated receptor activity; • growth factor binding; • microfibril binding; • transforming growth factor beta binding; • extracellular matrix structural constituent;
Cydrannau o'r gell	• GO:0005578 extracellular matrix; • microfibril; • extracellular space; • endoplasmic reticulum lumen; • extracellular region; • GO:0009327 protein-containing complex; • collagen-containing extracellular matrix;
Prosesau biolegol	• ventricular septum development; • sequestering of TGFbeta in extracellular matrix; • coronary vasculature development; • aorta development; • transmembrane receptor protein serine/threonine kinase signaling pathway; • post-translational protein modification; • regulation of transforming growth factor beta activation;
	Sources:Amigo / QuickGO
Orthologau
	4052
	n/a
	ENSG00000049323
	n/a
	Q14766
	n/a
	NM_000627; NM_001166264; NM_001166265; NM_001166266; NM_206943
	n/a
	NP_000618; NP_001159736; NP_001159737; NP_001159738; NP_996826
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LTBP1 yw LTBP1 a elwir hefyd yn Latent transforming growth factor beta binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p22.3.^[2]

Llyfryddiaeth

"Latent transforming growth factor-beta binding protein-1 in circulating plasma as a novel biomarker for early detection of hepatocellular carcinoma. ". Int J Clin Exp Pathol. 2015. PMID 26884881.
"Dental pulp stem cells suppress the proliferation of lymphocytes via transforming growth factor-β1. ". Hum Cell. 2015. PMID 25605036.
"Cooperative effects of EGF, FGF, and TGF-β1 in prostate stromal cells are different from responses to single growth factors. ". Life Sci. 2015. PMID 25529149.
"No association of the TGF-β1 29T/C polymorphism with breast cancer risk in Caucasian and Asian populations: evidence from a meta-analysis involving 55,841 subjects. ". Asian Pac J Cancer Prev. 2014. PMID 25374198.
"Association of transforming growth factor-Beta 1 promoter variant -509 c/t with bronchial asthma in South Indian population.". Inflammation. 2015. PMID 25359706.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] LTBP1 - Cronfa NCBI

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[2]