LTBR

LTBR
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1RF3, 4MXW
Dynodwyr
Cyfenwau	LTBR, CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3, lymphotoxin beta receptor
Dynodwyr allanol	OMIM: 600979 HomoloGene: 1753 GeneCards: LTBR
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • tumor necrosis factor-activated receptor activity; • identical protein binding; • ubiquitin protein ligase binding;
Cydrannau o'r gell	• integral component of membrane; • bilen; • Cellbilen; • integral component of plasma membrane; • Golgi apparatus;
Prosesau biolegol	• myeloid dendritic cell differentiation; • tumor necrosis factor-mediated signaling pathway; • positive regulation of JNK cascade; • multicellular organism development; • cellular response to mechanical stimulus; • response to lipopolysaccharide; • regulation of cell population proliferation; • positive regulation of extrinsic apoptotic signaling pathway; • inflammatory response; • GO:0022415 viral process; • GO:0072468 signal transduction; • GO:0097285 apoptotic process; • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response; • positive regulation of I-kappaB kinase/NF-kappaB signaling; • hematopoietic or lymphoid organ development;
	Sources:Amigo / QuickGO
Orthologau
	4055
	n/a
	ENSG00000111321
	n/a
	P36941
	n/a
	NM_001270987; NM_002342
	n/a
	NP_001257916; NP_002333
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LTBR yw LTBR a elwir hefyd yn Lymphotoxin beta receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12p13.31.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LTBR.

CD18
TNFCR
TNFR3
D12S370
TNFR-RP
TNFRSF3
TNFR2-RP
LT-BETA-R
TNF-R-III

Llyfryddiaeth

"Association of LTβR gene polymorphisms with prostate volume in benign prostatic hyperplasia in the Korean population. ". Genet Mol Res. 2015. PMID 26782510.
"Activation of lymphotoxin-beta receptor enhances the LPS-induced expression of IL-8 through NF-κB and IRF-1. ". Immunol Lett. 2015. PMID 25887375.
"Pillars article: A lymphotoxin-B-specific receptor. Science. 1994. 264: 707-710. ". J Immunol. 2014. PMID 24563505.
"Dimerization of LTβR by LTα1β2 is necessary and sufficient for signal transduction. ". Proc Natl Acad Sci U S A. 2013. PMID 24248355.
"Association between lymphotoxin beta receptor gene polymorphisms and IgA nephropathy in Korean children.". Immunol Invest. 2012. PMID 22417320.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] LTBR - Cronfa NCBI

[1]

[2]